Mesna
(Generic Name) Other Names: Mesne
About This Drug
Mesna is a drug given intravenously (IV), with and after ifosfamide or cyclophosphamide. Mesna is given to prevent bladder irritation and bleeding that ifosfamide and cyclophosphamide frequently cause.
Possible Side Effects
With higher doses of mesna, the following side effects are more common:
- nausea
- headache
- fatigue
- diarrhea
- taste changes
- pain in arms or legs
- low blood pressure
- Allergic reactions to this drug are rare, but may occur in some patients who receive this drug. Signs of allergic reaction are shortness of breath, rash or itching, dizziness or lightheadedness, or palpitations (feeling your heart beat rapidly).
Food and Drug Interactions
There are no known interactions of mesna and any food. This drug may interact with other medications. Tell your doctor and pharmacist all the medications that you are currently taking.
When to Call the Doctor
Call your doctor or nurse immediately if you have any of the following symptoms:
- shortness of breath
- rash or itching
- dizziness or lightheadedness
- palpitations
Call your nurse or doctor as soon as possible if you have any of the following symptoms:
- diarrhea of five to six stools in a day or diarrhea with weakness or lightheadedness
- nausea unrelieved by prescribed medication
- bleeding when urinating
- painful urination
- headaches
- pain in the arms or legs unrelieved by prescribed medication