High-Risk Ovarian Cancer Program at Magee

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High-Risk Ovarian Cancer Program Overview

Your risk of developing ovarian cancer may be higher if you carry a specific mutation in your genes.

High-risk women benefit from screening and close monitoring to diagnose ovarian cancer early, when it's more treatable.

If you're concerned about the risk of developing ovarian cancer, the High-Risk Ovarian Cancer Program at Magee-Womens Hospital of UPMC offers the following evaluation methods and recommendations:

  • an ovarian cancer risk assessment
  • screening tests
  • genetic counseling and testing
  • education about ovarian cancer risk and potential implications for family members 
  • a personalized surveillance plan
  • prevention strategies

You also have the option to participate in ovarian cancer research studies to take advantage of the most recent treatment options available.

For more information about the High-Risk Gynecologic Cancer Program, or to schedule an appointment, call 412-623-3425.

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Ovarian Cancer Risk Assessment

The experts at the High-Risk Ovarian Cancer Program will conduct a brief cancer risk assessment to:

  • evaluate your risk factors for developing ovarian cancer
  • help you understand how various factors influence your risk
  • provide information on appropriate ways to reduce that risk

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Screening Tests for Ovarian Cancer

If you're at an increased risk for developing ovarian cancer, it's important to monitor your health.

Even though you may not be experiencing symptoms, screening tests can detect early stage signs of ovarian cancer. And, the sooner you're diagnosed and treated, the better your chance for recovery.

Ovarian cancer screening tests may include:

Pelvic exam by your PCP or gynecologist

An examination of the vagina, rectum, and lower abdomen can determine if detectable masses or growths are present.

Experts at the High-Risk Ovarian Cancer Program work with your physicians to better determine your risk of developing ovarian cancer.

Transvaginal ultrasound (sonography)

An ultrasound of the vagina uses high-frequency sound waves to:

  • capture images of internal reproductive organs and tissues
  • produce real-time pictures of tumors

Researchers are currently studying the use of transvaginal ultrasound as a screening tool for early ovarian cancer detection.

CA125 serum tumor marker

A blood test that measures levels of CA125 — a protein that's found in greater concentration in tumor cells, particularly ovarian cancer cells.

It's currently identified in high-risk patients to determine if ovarian cancer cells may be present.

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Genetic Counseling and Testing for Ovarian Cancer

Researchers have identified certain genes that, when changed or mutated, increase your risk for developing ovarian cancer.

Depending on your personal and family history, you may decide to have the experts at the Cancer Genetics Program study your specific genes.

Genetic testing information may help you:

  • learn if you have an increased likelihood of developing ovarian cancer
  • discover if inherited factors have contributed to yours or a family member's cancer
  • make more informed medical decisions

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Make an Appointment

Call 412-623-3425 to schedule an appointment at the High-Risk Gynecologic Cancer Program.

We're located at Hillman Cancer Center, 5115 Centre Ave., in the Shadyside area of Pittsburgh, Pa.

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