Research and Clinical Trials
UPMC has long been a leader in cardiovascular care, with a rich history in clinical research and innovation.
Our patients benefit from having access to some of the most current and promising procedures and medications.
Our strength in cardiovascular research is the result of two things:
- Our close affiliation with the University of Pittsburgh, our academic partner, which remains one of the top 10 institutions in the United States funded by the American Heart Association.
- Our very large clinical practice.
Our expertise in diagnosing and treating a large and diverse volume of patients, along with our commitment to advancing scientific discovery, has helped us to develop a very strong catalog of research on cardiovascular disease.
>>Search for a cardiovascular clinical trial
Exploring new cardiovascular treatments
Today, our clinicians, surgeons, and physician researchers are:
- Exploring and employing new technologies and treatments to find better ways to treat cardiovascular disease.
- Delving into basic science questions to find out why people develop certain types of cardiovascular disease in the first place.
- Trying to understand the genetics of heart disease, which may help us develop therapies to limit the severity — or even prevent — the disease.
Ongoing research efforts
Cardiology clinical research
The UPMC Division of Cardiology receives millions of dollars in funding each year to conduct important cardiovascular research.
This research has expanded our understanding of the basic elements of cardiovascular development, anatomy, pharmacology, and control, enabling us to develop new approaches to diagnose and treat cardiovascular disease.
While we maintain a broad catalog of research, the major strengths of our research program include:
- heart failure
- molecular imaging using echocardiography
- sudden cardiac death
- translational genetics
- heart failure/stem cell research
- noninvasive imaging
- vascular biology
Cardiology research » learn more from the Division of Cardiology.
UPMC Shadyside is host to several industry- and NIH-sponsored clinical cardiology trials.
Clinical trials » learn more from UPMC Shadyside
Cardiothoracic surgery clinical research
The UPMC Department of Cardiothoracic Surgery also conducts novel research, with a focus on the following areas:
- antirejection techniques for heart and lung transplantation
- ventricular-assist device therapy to help the heart heal itself
- autologous stem cell injections into damaged heart tissue to improve ejection fraction in patients with heart failure
- minimally invasive surgical techniques to reduce length of hospital stays
Cardiothoracic research » learn more from the Division of Cardiac Surgery.
Vascular surgery clinical research
The Division of Vascular Surgery’s physicians and scientists collaborate to explore and develop new and exciting treatments and technologies in the field of vascular medicine and surgery. The scope of research involves bioengineering, molecular biology, gene therapy, methods of inhibiting new intimal hyperplasia, and other aspects of vascular biology, especially in these areas:
- carotid stenting
- deep vein thrombosis
- peripheral vascular disease
- thoracic and abdominal aneurysms
- other venous conditions
Vascular surgery research » learn more from the Division of Vascular Surgery
The benefits of clinical trials
Clinical research studies, or clinical trials, are crucial to the advancement of medical knowledge.
Through clinical trials, we:
- learn how a new medicine or treatment works in people
- find out what works and what doesn’t work
- discover new and better ways of preventing, diagnosing, and treating heart and vascular diseases and conditions
Find specific clinical research trials from the University of Pittsburgh Office of Clinical Research.
Read how participation in a clinical trial is helping one of our patients.