Regional Chemotherapy for Liver Tumors

Regional Therapy with Transarterial Chemoembolization and Internal Radiation with Yttrium-90 Spheres

At the UPMC Liver Cancer Center, the preferred approach for inoperable liver tumors that are confined to the liver, is either regional therapy with transarterial chemoembolization (TACE) or internal radiation with yttrium-90 spheres.

Bile duct cancer

For people with metastatic cholangiocarcinoma (bile duct cancer), we may recommend systemic chemotherapy.

Metastatic colon/rectal cancer

For people with metastatic colon/rectal cancer to the liver, it's very common that you may have received some form of prior systemic chemotherapy.

After a surgical resection for a hepatic metastases from colon cancer, the liver surgeons at the UPMC Liver Cancer Center, together with your local oncologist, will discuss options with you and help you decide if postoperative (adjuvant) systemic chemotherapy is the best approach.

Hepatocellular carcinoma

For people with widespread hepatocellular carcinoma (HCC), systemic chemotherapy is generally not recommended due to poor response rates.

If a person with HCC develops localized extra-hepatic spread to a lymph node, bone, or adrenal gland, then focused radiation therapy occasionally may be recommended.

¬©  UPMC | Affiliated with the University of Pittsburgh Schools of the Health Sciences
Supplemental content provided by A.D.A.M. Health Solutions. All rights reserved.

For help in finding a doctor or health service that suits your needs, call the UPMC Referral Service at 412-647-UPMC (8762) or 1-800-533-UPMC (8762). Select option 1.

UPMC is an equal opportunity employer. UPMC policy prohibits discrimination or harassment on the basis of race, color, religion, ancestry, national origin, age, sex, genetics, sexual orientation, marital status, familial status, disability, veteran status, or any other legally protected group status. Further, UPMC will continue to support and promote equal employment opportunity, human dignity, and racial, ethnic, and cultural diversity. This policy applies to admissions, employment, and access to and treatment in UPMC programs and activities. This commitment is made by UPMC in accordance with federal, state, and/or local laws and regulations.

Medical information made available on UPMC.com is not intended to be used as a substitute for professional medical advice, diagnosis, or treatment. You should not rely entirely on this information for your health care needs. Ask your own doctor or health care provider any specific medical questions that you have. Further, UPMC.com is not a tool to be used in the case of an emergency. If an emergency arises, you should seek appropriate emergency medical services.

For UPMC Mercy Patients: As a Catholic hospital, UPMC Mercy abides by the Ethical and Religious Directives for Catholic Health Care Services, as determined by the United States Conference of Catholic Bishops. As such, UPMC Mercy neither endorses nor provides medical practices and/or procedures that contradict the moral teachings of the Roman Catholic Church.

© UPMC
Pittsburgh, PA, USA UPMC.com