How can we help you?
Schedule anappointment »
Ask a question »
Request our expertopinion »
412-647-3685(within the U.S.)
This freelance writer faced the ultimate deadline, as her team of UPMC neurosurgeons raced to remove a tennis-ball sized tumor using the Neuroendoport® approach. Discharged after two days, she began the next stage of treatment and was soon back to her normal routine.
Read more »
Glioblastoma, also known as glioblastoma multiforme, is the most common and most aggressive type of primary brain cancer.
It is a subtype of astrocytoma, which arises from the brain tissue and resembles astrocytes, the supportive cells that encircle and protect the nerve cells in the brain.
Glioblastomas are remarkably difficult to treat.
However, surgical removal of the glioblastoma by craniotomy can be beneficial for some people, both to alleviate symptoms associated with the tumor and to extend survival and life expectancy following radical removal.
After a diagnosis of glioblastoma, all patients will need several forms of medical care, including:
In most patients, image-guided craniotomy — often accompanied by careful preoperative or intraoperative brain mapping using MEG — may improve our ability to remove the glioblastoma safely.
To make the diagnosis of glioblastoma, your doctor will ask you about your symptoms and order imaging tests.
Glioblastoma symptoms may include:
Doctors can identify glioblastomas using imaging studies, such as MRI or CT scans.
Surgical removal or biopsy are standard initial treatment strategies for newly diagnosed or recurrent glioblastomas.
Commonly, we use radiation therapy and chemotherapy in conjunction with surgery to treat a glioblastoma.
The UPMC neurosurgical team will carefully evaluate you — looking at your condition from every direction — to find the path that is least disruptive to your brain, critical nerves, and ability to return to normal functioning.
Our neurosurgeons often use image-guided surgery, accompanied by pre- or intraoperative brain mapping, to improve our ability to remove the glioblastoma safely.
Despite an initial multipronged treatment for glioblastomas, some people with residual tumor or tumor recurrence often need additional options.
One option is Gamma Knife radiosurgery, a painless method to non-invasively boost the effectiveness of radiation delivered to the tumor.
UPMC is the nation's leading provider of Gamma Knife procedures. Our team has treated more than 12,000 patients with tumors, vascular malformations, pain, and functional problems.
Our team may also perform stereotactic radiosurgery using the Cyberknife or other linear accelerator-based systems.
Fractionated radiation is commonly used to treat glioblastomas, either alone or in combination with surgery and/or chemotherapy.
We deliver radiation therapy:
Chemotherapy uses drugs to stop the growth of glioblastoma cancer cells and may be taken by mouth, injected, or placed directly into the brain tumor site.
Cutting-edge brain imaging technology developed at the University of Pittsburgh and UPMC is helping to save cancer patients' lives.
Read the full story on CBS Pittsburgh.
Affiliated with the University of Pittsburgh Schools of the Health Sciences
| Supplemental content provided by Healthwise, Incorporated. To learn more, visit www.healthwise.org
For help in finding a doctor or health service that suits your needs, call the UPMC Referral Service at 412-647-UPMC (8762) or 1-800-533-UPMC (8762). Select option 1.
UPMC is an equal opportunity employer. UPMC policy prohibits discrimination or harassment on the basis of race, color, religion, ancestry, national origin, age, sex, genetics, sexual orientation, gender identity, marital status, familial status, disability, veteran status, or any other legally protected group status. Further, UPMC will continue to support and promote equal employment opportunity, human dignity, and racial, ethnic, and cultural diversity. This policy applies to admissions, employment, and access to and treatment in UPMC programs and activities. This commitment is made by UPMC in accordance with federal, state, and/or local laws and regulations.
Medical information made available on UPMC.com is not intended to be used as a substitute for professional medical advice, diagnosis, or treatment. You should not rely entirely on this information for your health care needs. Ask your own doctor or health care provider any specific medical questions that you have. Further, UPMC.com is not a tool to be used in the case of an emergency. If an emergency arises, you should seek appropriate emergency medical services.
Pittsburgh, PA, USA | UPMC.com