Our surgeons are among the most experienced in the world in treating an array of neurosurgical conditions.
Read about our surgical team >
Inverted papillomas are nasal tumors that originate in the mucosal membrane of the nasal cavity and paranasal sinuses.
Papillomas are benign epithelial tumors that grow outward in fingerlike projections in the nose. In inverted papillomas, these projections grow inward and into the underlying bone. These tumors are locally aggressive, often recur, and can become malignant (cancerous).
Squamous cell carcinoma is the most common malignancy associated with inverted papillomas.
Symptoms of inverted papillomas may include:
At UPMC, the preferred surgical treatment for inverted papilloma is the Endoscopic Endonasal Approach (EEA). This innovative, minimally invasive technique uses the nose and nasal cavities as natural corridors to access hard-to-reach or previously inoperable tumors. Surgeons can then remove the inverted papilloma. Benefits of EEA include:
Most inverted papillomas can be found during a physical examination of the nasal and sinus cavities. They have a reddish-grey appearance and may bleed when touched.
The septum may be bowed by the mass of the inverted papilloma. Facial swelling and proptosis (bulging of the eyes) may accompany lesions that have expanded considerably.
During the physical exam, your doctor will ask about any symptoms you are having.
Symptoms of inverted papilloma may include:
Imaging studies reveal the extent to which the inverted papillomas have spread and the degree of bone destruction. An MRI is preferred because it allows inverted papillomas to be better distinguished from other types of lesions.
Biopsy is necessary to make a definitive diagnosis.
Surgery is the primary treatment for inverted papillomas. Because of the high recurrence rate (40 to 80 percent), early, aggressive surgery to remove the papilloma usually is recommended.
Inverted papillomas of the sinuses, nasal cavity, and skull base may be approached directly using the Endoscopic Endonasal Approach (EEA).
This state-of-the-art, minimally invasive approach allows surgeons to access the tumor through the natural corridor of the nose, without making an open incision. Surgeons then remove the inverted papilloma through the nose and nasal cavities.
EEA offers the benefits of no incisions to heal, no disfigurement, and a faster recovery time.
Endoscopic approaches such as EEA have good success rates in preventing recurrence and better cosmetic outcomes than traditional open surgical approaches.
How can we help you?
Schedule anappointment >
Ask a question >
Request our expertopinion >
1-877-986-9862(within the U.S.)
Affiliated with the University of Pittsburgh Schools of the Health Sciences
Supplemental content provided by
A.D.A.M. Health Solutions. All rights reserved.
For help in finding a doctor or health service that suits your needs, call the UPMC Referral Service at 412-647-UPMC (8762) or 1-800-533-UPMC (8762). Select option 1.
UPMC is an equal opportunity employer. UPMC policy prohibits discrimination or harassment on the basis of race, color, religion, ancestry, national origin, age, sex, genetics, sexual orientation, marital status, familial status, disability, veteran status, or any other legally protected group status. Further, UPMC will continue to support and promote equal employment opportunity, human dignity, and racial, ethnic, and cultural diversity. This policy applies to admissions, employment, and access to and treatment in UPMC programs and activities. This commitment is made by UPMC in accordance with federal, state, and/or local laws and regulations.
Medical information made available on UPMC.com is not intended to be used as a substitute for professional medical advice, diagnosis, or treatment. You should not rely entirely on this information for your health care needs. Ask your own doctor or health care provider any specific medical questions that you have. Further, UPMC.com is not a tool to be used in the case of an emergency. If an emergency arises, you should seek appropriate emergency medical services.
For UPMC Mercy Patients: As a Catholic hospital, UPMC Mercy abides by the Ethical and Religious Directives for Catholic Health Care Services, as determined by the United States Conference of Catholic Bishops. As such, UPMC Mercy neither endorses nor provides medical practices and/or procedures that contradict the moral teachings of the Roman Catholic Church.
Pittsburgh, PA, USA UPMC.com