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Our Experts at the UPMC Adult Sickle Cell Disease Program

Our multidisciplinary team provides comprehensive clinical services to help you efficiently manage your sickle cell disease or thalassemia.

Enrico Novelli, MD
Medical Director, UPMC Adult Sickle Cell Disease Program

Enrico Novelli, MD, received his medical degree from the Universita´ degli Studi di Milano in Milan, Italy. He completed his residency in internal medicine with a subspecialty in hematology oncology at the University of Pittsburgh Medical School.

After completing his residency, Dr. Novelli volunteered as the Internal Medicine Specialist at Lilongwe Central Hospital in Malawi, Africa.

His experience there solidified his commitment to developing clinical expertise and research projects aimed at alleviating the disease burdens of global populations with limited access to modern health care. Thus, Dr. Novelli’s clinical interests focus on the various aspects of sickle cell disease and disorders of hemostasis.

He is a member of the American Society of Hematology and also has a keen interest in developing global health research and training initiatives in the field of Tropical Hematology.

Specialized care for adults with sickle cell disease

Board-certified in internal medicine and hematology, Dr. Novelli's services include:

  • Outpatient care — He provides direct, specialized outpatient care for adults with sickle cell disease and other hemoglobinopathies at the Hillman Cancer Center weekly clinic.
  • Inpatient care — He interacts with the hospital’s internal medicine and hematology consult teams, giving people truly comprehensive inpatient care.
  • Consults — He also offers specialized medical consultation services on a case-by-case basis to other medical providers who treat adults with sickle cell disease.

Dr. Novelli also facilitates clinical trials for identifying new therapies and drugs for treating sickle cell disease.

Learn more about Dr. Novelli's sickle cell disease research interests.

Mark Gladwin, MD

Mark Gladwin, MD, received his medical degree from the University of Miami Medical Education Honors Program. He completed his internship and served as chief resident during his residency at Oregon Health Sciences University.

He then joined the National Institutes of Health (NIH) as a critical care fellow and later served as Chief of the Pulmonary and Vascular Medicine Branch within the NHLBI of NIH for over a decade. During his tenure as an NIH Branch Chief, Dr. Gladwin’s research activities led to four scientific discoveries and have resulted in over 150 published peer-reviewed manuscripts, 25 approved human subject protocols, and over 1,000 patient protocol enrollments at the NIH Clinical Center.

In 2008, the University of Pittsburgh School of Medicine named Gladwin Chief of the Pulmonary, Allergy, and Critical Care Medicine Division and Director of the Vascular Medicine Institute.

Dr. Gladwin's current clinical research interests focus on pulmonary hypertension and other pulmonary complications of sickle cell disease. Through his research and clinical trials, Dr. Gladwin will continue working tirelessly toward the development of new therapies and, ultimately, a widely available cure for sickle cell disease.

Seen and heard — Dr. Gladwin in the news

Other Members of the Sickle Cell Disease Care Team

Dominique Stevens-Young, MSW

Stevens-Young is a licensed clinical social worker who's been caring for adults with sickle cell disease since 2001.

As senior clinical social worker and program administrator for the UPMC Adult Sickle Cell Disease Program, she:

  • Conducts comprehensive assessments of patients’ psychosocial needs.
  • Coordinates ongoing psychosocial care and support services for adults with sickle cell disease.
  • Provides social service resources and education to people with hemoglobinopathies and their families.

Christine Evans, PA-C

Evans, a physician assistant, works as a liaison between the UPMC sickle cell disease consult service and the internal medicine or subspecialist teams in both clinical and inpatient settings.

Evelyn Wrzosek, RN

Wrzosek is the UPMC Adult Sickle Cell Disease Program's collaborative nurse for outpatient services. Caring for people with chronic disease since 1997, she responds to telephone calls from patients and their families regarding sickle cell disease treatment needs, complications, and other medical issues.

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