Clinical Trials for Women with Urinary Urge Incontinence

Are you one of the many American women that experiences frequent urge incontinence or leaks urine twice or more each day?

If so, and you have tried medicines and therapies that have not worked, you might be a candidate for the ROSETTA Study: Refractory Overactive Bladder: Sacral Neuromodulation v. BoTulinum Toxin Assessment.

What is the ROSETTA Study?

The Rosetta study will compare the effect of two therapies in women who have bothersome urinary urge incontinence and who have failed to get relief from oral medications. The two therapies are:

  • Botox® which is injected into the bladder muscle
  • InterStim® Therapy

Who is eligible for ROSETTA?

  • Women with symptoms of urge incontinence or overactive bladder
  • At least 21 years of age or older
  • Experience urge urine leakage two or more times per day
  • Have tried at least two medications  for overactive bladder or urge incontinence

Women who participate in this study will be asked to attend in-person visits, complete telephone calls, symptoms questionnaires, and three day bladder diaries over the course of two years after treatment. 

For further information about the ROSETTA study please contact the research coordinator at 412-641-6679 or email

Patients will be seen at Magee-Womens Hospital of UPMC in Suite 5600 and will be compensated for participation.

Contact Us

Women's Center for Bladder and Pelvic Health
Magee-Womens Hospital of UPMC
300 Halket Street
Pittsburgh, PA 15213


Office Hours: 8 a.m. - 4:30 p.m., Monday through Friday

  • Magee-Womens Hospital of UPMC
  • 300 Halket St.
  • Pittsburgh, PA 15213-3180
  • Main Hospital/Operator:
  • To find a physician, or schedule an appointment:
    1-866-MyMagee (696-2433)
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