Navigate Up
UPMC/University of Pittsburgh Schools of the Health Sciences
Senior Manager
Telephone: 412-578-9193 or 412-624-3212

Patients and medical professionals may call 1-800-533-UPMC (8762) for more information.

J. Mark Braughler Joins Rheogene Inc. As Vice President Of Therapeutics

Will Lead RheoGene's Office of Clinical Applications in Pittsburgh

NORRISTOWN, Pa., May 25, 2004 RheoGene Inc. is pleased to announce that J. Mark Braughler, Ph.D., has joined its executive management team as vice president of therapeutics. Dr. Braughler will head RheoGene's Clinical Applications office and laboratory in Pittsburgh, where he will direct RheoGene's preclinical and clinical development programs and oversee RheoGene's academic and institutional research collaborations.

Dr. Braughler comes to RheoGene from Paradigm Genetics, Inc. (Research Triangle Park, N.C.) where he was vice president of business development - healthcare. Dr. Braughler joined Paradigm Genetics following its acquisition of TissueInformatics Inc. (Pittsburgh, Pa.), where he had served as senior vice president of business development and acting COO.

During his tenure at TissueInformatics, he established and guided research and commercial programs in the development of automated pathology software as well as drug target discovery in diabetes, obesity and aging that yielded a number of novel drug targets and several products. Prior to joining TissueInformatics, Dr. Braughler was CEO and President of Argonex Inc. (Charlottesville, Va.) where he was instrumental in the formation of RHeoGene LLC, a joint venture between Rohm and Haas Co. and Argonex Inc. that operated between 1999 and 2002, and was the predecessor company of RheoGene Inc. Prior to joining Argonex, he held several management positions at Pharmacia & Upjohn, including vice president of business development.

"Mark represents an important and valuable addition to the RheoGene team as we transition from a platform tools company to a broad-based human therapeutics company," stated Tom Tillett, president and CEO of RheoGene. "Mark brings not only pharmaceutical drug discovery and development expertise to RheoGene, but also extensive biotechnology business experience that will be critical to helping us translate the competitive advantages of our RheoSwitch technology into successful therapies for cell- and gene-based medicines."

Establishing a clinical laboratory in Pittsburgh will enable the company to work closely with its collaborators to more rapidly advance products based on its proprietary RheoSwitch and RheoPlex inducible gene regulation technology into preclinical and clinical testing.

"I am very pleased to be joining RheoGene and to have the opportunity to be affiliated with such a talented group of scientists and leaders," said Dr. Braughler. "RheoGene's breakthrough technology platform, comprehensive patent estate and impressive research progress over the past several years position the company for rapid progress in the therapeutic marketplace. The company's affiliation with the University of Pittsburgh Medical Center (UPMC) and my role in strengthening RheoGene's presence in Pittsburgh represents an excellent opportunity to continue to establish a successful biotechnology presence in the area with a national and international reach."

RheoGene has established a number of cell and gene therapy collaborations with researchers and clinicians at UPMC's McGowan Institute for Regenerative Medicine, the University of Pittsburgh Cancer Institute and the University of Pittsburgh. Overall, RheoGene has initiated over 20 therapeutic and disease collaborations at UPMC and other leading institutions in the areas of cancer, regenerative medicine, CNS and cardiovascular disorders and infectious diseases.

About RheoGene Inc.
RheoGene Inc. is the source of advanced products, applications and technologies that regulate gene expression for the development of safe and effective therapeutics. RheoGene delivers customized inducible gene expression products for pharmaceutical discovery, human therapeutics, biotherapeutics production and agriculture. RheoGene Inc. is a wholly owned subsidiary of RheoGene Holdings Inc., a wholly owned affiliate of the University of Pittsburgh Medical Center. The company's operations are located in Norristown, Pa. For more information, visit http://www.rheogene.com.

©  UPMC | Affiliated with the University of Pittsburgh Schools of the Health Sciences
Supplemental content provided by A.D.A.M. Health Solutions. All rights reserved.

For help in finding a doctor or health service that suits your needs, call the UPMC Referral Service at 412-647-UPMC (8762) or 1-800-533-UPMC (8762). Select option 1.

UPMC is an equal opportunity employer. UPMC policy prohibits discrimination or harassment on the basis of race, color, religion, ancestry, national origin, age, sex, genetics, sexual orientation, marital status, familial status, disability, veteran status, or any other legally protected group status. Further, UPMC will continue to support and promote equal employment opportunity, human dignity, and racial, ethnic, and cultural diversity. This policy applies to admissions, employment, and access to and treatment in UPMC programs and activities. This commitment is made by UPMC in accordance with federal, state, and/or local laws and regulations.

Medical information made available on UPMC.com is not intended to be used as a substitute for professional medical advice, diagnosis, or treatment. You should not rely entirely on this information for your health care needs. Ask your own doctor or health care provider any specific medical questions that you have. Further, UPMC.com is not a tool to be used in the case of an emergency. If an emergency arises, you should seek appropriate emergency medical services.

For UPMC Mercy Patients: As a Catholic hospital, UPMC Mercy abides by the Ethical and Religious Directives for Catholic Health Care Services, as determined by the United States Conference of Catholic Bishops. As such, UPMC Mercy neither endorses nor provides medical practices and/or procedures that contradict the moral teachings of the Roman Catholic Church.

© UPMC
Pittsburgh, PA, USA UPMC.com