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Cerner and UPMC Launch Innovation Initiative

KANSAS CITY, Mo. and PITTSBURGH — May 1, 2006 — Cerner Corp. (NASDAQ: CERN) and the University of Pittsburgh Medical Center (UPMC) announced today that they have agreed to establish a three-year joint initiative to create and commercialize innovative healthcare information technology solutions. The agreement, which brings together one of the most renowned academic medical centers with the nation’s leading provider of healthcare IT, will leverage both companies’ respective strengths to research, develop and deliver the latest technological advances in medicine.

“UPMC has a long history of innovation and delivering emerging information technology solutions,” said Dan Drawbaugh, UPMC’s chief information officer. “Through collaborations like this one, we can help transform the delivery of healthcare industrywide while creating new revenue to support UPMC’s core clinical and research mission.”

The initiative’s board of directors, with equal representation from both companies, will oversee the selection and development of projects. The shared efforts may include innovations in supply chain, e-medicine and community health.

“Cerner and UPMC share the vision and the entrepreneurial spirit that innovation demands,” said Neal Patterson, Cerner chairman and CEO. “We are excited to collaborate with this industry leading organization to develop new ways to elevate healthcare delivery around the world.”

The first of its kind for Cerner, this joint initiative provides a strategic opportunity for both companies to build upon their respective missions to improve the quality, cost and delivery of healthcare. Unmatched by its competitors, Cerner has invested more than $1.2 billion in research and development since 1995 and plans to invest a comparable amount over the next five years. Likewise, UPMC is consistently recognized as a leader in adopting new technologies to transform the delivery of healthcare. It has been named one of the “100 Most Wired” health systems in the United States for seven consecutive years by the American Hospital Association.

Cerner and UPMC have worked together for more than five years to enhance patient safety and the overall quality of care throughout the health system. For instance, Children’s Hospital of Pittsburgh, the specialty hospital devoted to pediatric medicine at UPMC, implemented Cerner’s electronic health record and computerized physician order entry (CPOE) system in October 2002. Since the implementation, Children’s adverse drug events (ADEs) have fallen 50 percent per year and transcription errors have been virtually eliminated.

In addition, UPMC recently signed an agreement to implement Cerner’s genomic information solution, Millennium Helix ™. The one-of-a-kind solution responds to the unique processes and IT needs of the molecular diagnostics laboratory and provides immediate access to genetic information, allowing physicians to design a person-specific report that will assist them in the critical care of their patients. In combination with the work of UPMC’s leading researchers and scientists, the solution will help advance discoveries in genomics.

The University of Pittsburgh Medical Center (UPMC) is the largest integrated healthcare delivery system in Pennsylvania and one of the leading nonprofit medical centers in the country. It is consistently ranked as one of the nation’s best hospitals by U.S. News & World Report. With 40,000 employees, it is the largest employer in western Pennsylvania. UPMC spans the full spectrum of healthcare delivery with its network of 19 hospitals, more than 400 outpatient sites and doctors' offices, and an insurance division.

Cerner Corp. is taking the paper chart out of healthcare, eliminating error, variance and waste in the care process. With more than 1,500 clients worldwide, Cerner is the leading supplier of healthcare information technology. The following are trademarks of Cerner: Cerner, Millennium Helix, Cerner’s logo. NASDAQ: CERN. www.cerner.com.

This release contains forward-looking statements that involve a number of risks and uncertainties. It is important to note that the Company's performance, and actual results, financial condition or business could differ materially from those expressed in such forward-looking statements. The words “will”, “may”, “plans” or the negative of these words, variations thereof or similar expressions are intended to identify such forward-looking statements. Factors that could cause or contribute to such differences include, but are not limited to: the possibility of product-related liabilities; potential claims for system errors and warranties; the possibility of interruption at our data centers or client support facilities; our proprietary technology may be subjected to infringement claims or may be infringed upon; recruitment and retention of key personnel; risks related to third party suppliers; changing political, economic and regulatory influences; government regulation; significant competition and market changes; variations in the our quarterly operating results; and, failure of the parties to achieve the intended benefits. Additional discussion of these and other factors affecting the Company's business is contained in the Company's periodic filings with the Securities and Exchange Commission. The Company undertakes no obligation to update forward-looking statements to reflect changed assumptions, the occurrence of unanticipated events or changes in future operating results, financial condition or business over time.

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