Other Names: Trelstar®
About This Drug
Triptorelin is used to treat cancer. It is given in the muscle in the buttock.
Possible Side Effects (More Common)
- Swelling of your legs, ankles and/or feet
- Generalized weakness and discomfort (aches or pains)
- Hot flashes or sudden skin flushing may happen. You may also feel warm or red.
- Difficulty achieving or maintain an erection
- Decrease in size of testicles
- Increase in disease symptoms
Possible Side Effects (Less Common)
- Urinary retention (not able to pass urine). You may not fully drain your bladder of urine.
- Your heart tissue can be harmed. This may cause your heart to beat in a way that is not normal. Your doctor may order an EKG to check this.
- Increase in blood sugar and risk for diabetes
Allergic reactions, including anaphylaxis are rare but may happen in some patients. Signs of allergic reaction to this drug may be swelling of the face, feeling like your tongue or throat are swelling, trouble breathing, rash, itching, fever, chills, feeling dizzy, and/or feeling that your heart is beating in a fast or not normal way. If this happens, do not take another dose of this drug. You should get urgent medical treatment.
Treating Side Effects
- Damage to the heart is rare. Your doctor will check your heart function as needed.
- Wearing clothes that are loose and layered can help decrease hot flashes.
Food and Drug Interactions
There are no known interactions of triptorelin with food. This drug may interact with other medications. Tell your doctor and pharmacist about all the medication and dietary supplements (vitamins, minerals, herbs, and others) that you are currently taking. The safety and effectiveness of dietary supplements and alternative diets are often unknown. Using these might unexpectedly affect your cancer or interfere with your treatment. Until more is known, you should not use dietary supplements or alternative diets without your cancer doctor's advice.
When to Call the Doctor
Call your doctor or nurse immediately if you have any of the following symptoms:
- Easy bleeding or bruising
- Wheezing or trouble breathing
- Rash or itching
- Feeling dizzy or lightheaded
- Feeling that your heart is beating in a fast or not normal way (palpitations)
- Loose bowel movements (diarrhea) more than 4 times a day or diarrhea with weakness or lightheadedness
- Blurred vision or other changes in eyesight
- Pain when passing urine; blood in urine
- Pain in your lower back or side
- Confusion or agitation
- Nausea that stops you from eating or drinking
- Throwing up more than 3 times a day
- Chest pain or symptoms of a heart attack. Most heart attacks involve pain in the center of the chest that lasts more than a few minutes. The pain may go away and come back. It can feel like pressure, squeezing, fullness, or pain. Sometimes pain is felt in one or both arms, the back, neck, jaw, or stomach. If any of these symptoms last 2 minutes, call 911.
- Symptoms of a stroke such as sudden numbness or weakness of your face, arm, or leg, mostly on one side of your body; sudden confusion, trouble speaking or understanding; sudden trouble seeing in one or both eyes; sudden trouble walking, feeling dizzy, loss of balance or coordination; or sudden, bad headache with no known cause. If you have any of these symptoms for 2 minutes, call 911.
- Signs of liver problems: dark urine, pale bowel movements, bad stomach pain, feeling very tired and weak, unusual itching, or yellowing of the eyes or skin.
Call your doctor or nurse as soon as possible if any of the following symptoms occur:
- Change in hearing, ringing in the ears
- Decreased urine
- Unusual thirst or passing urine often
- Pain in your mouth or throat that makes it hard to eat or drink
- Nausea that is not relieved by prescribed medicines
- Rash that is not relieved by prescribed medicines
- Heavy menstrual period that lasts longer than normal
- Numbness, tingling, decreased feeling or weakness in fingers, toes, arms, or legs
- Trouble walking or changes in the way you walk, feeling clumsy when buttoning clothes, opening jars, or other routine hand motions
- Swelling of legs, ankles, or feet
- Weight gain of 5 pounds in one week (fluid retention)
- Lasting loss of appetite or rapid weight loss of five pounds in a week
- Fatigue that interferes with your daily activities
- Headache that does not go away
- Painful, red, or swollen areas on your hands or feet.
- No bowel movement for 3 days or you feel uncomfortable
- Extreme weakness that interferes with normal activities
- Sexuality warning: This drug may cause difficulty in achieving or maintaining an erection.
- Pregnancy warning: This drug may have harmful effects on the unborn child, so effective methods of birth control should be used during your cancer treatment.
- Genetic counseling is available for you to talk about the effects of this drug therapy on future pregnancies. Also, a genetic counselor can look at the possible risk of problems in the unborn baby due to this medicine if an exposure happens during pregnancy.
- Breast feeding warning: Women should not breast feed during treatment because this drug could enter the breast milk and badly harm a breast feeding baby.
Last updated March 2016