Also part of the UPMC family:

Nilutamide (Generic Name)

UPMC Content 2

About This Drug​

Nilutamide is used to treat men with prostate cancer. It is given by mouth.

Possible Side Effects (More Common)

  • Hot flashes
  • Trouble seeing at night
  • Alcohol intolerance

Possible Side Effects (Less Common)

  • Trouble breathing or feeling short of breath
  • Increase in liver enzymes
  • High blood sugar
  • Your heart tissue can be harmed. This may cause your heart to beat in a way that is not normal. Your doctor may order an EKG to check this.
  • Weakened bones (osteoporosis)

Treating Side Effects

  • Your doctor may order an EKG to check your heart function.
  • Your doctor may order blood work to check your blood sugar level and liver function.
  • Your doctor may order bone mineral density testing to check the strength of your bones.

Important Information

  • The tablets should be taken with water.
  • Swallow the tablets whole.  Do not break, crush or chew the tablets. 

Food and Drug Interactions

There are no known interactions of nilutamide with food. This drug may interact with other medicines. Tell your doctor and pharmacist about all the medicines and dietary supplements (vitamins, minerals, herbs and others) that you are taking at this time. The safety and use of dietary supplements and alternative diets are often not known. Using these might affect your cancer or interfere with your treatment. Until more is known, you should not use dietary supplements or alternative diets without your cancer doctor's help. 

When to Call the Doctor

Call your doctor or nurse right away if you have any of these symptoms: 

  • Feeling that your heart is beating in a fast or not normal way

Call your doctor or nurse as soon as possible if any of these symptoms happen:

  • Trouble breathing, feeling short of breath
  • Trouble seeing at night or other changes in eyesight

Other Information

Nilutamide should not be taken by women or children.


Revised July 2014