Also part of the UPMC family:

Captopril (Generic Name)Other Names: Capoten®

UPMC Content 2

Dosage form

Oral tablets: 12.5 mg, 25 mg, 50 mg

About this drug

Captopril (CAP-toe-pril) is used to treat high blood pressure, congestive heart failure, and kidney problems in people with diabetes. This medicine is classified as an ACE (angiotensin converting enzyme) inhibitor.

Side effects

Common side effects are:

  • Cough
  • Diarrhea
  • Weakness
  • Nausea and vomiting
  • Rapid heart beat (palpitations)
  • Dizziness. Be careful while taking this drug. Driving and using machines can be dangerous if you’re not alert.

Rare side effects include:

  • Fever
  • Chills
  • Stomach pain
  • Skin rash
  • Trouble breathing or swallowing
  • Joint pain
  • Increased potassium levels
  • Passing less urine

If any of these side effects become severe or bother you, talk to your doctor. Do not take over-the-counter medicines for your symptoms.

Drug interactions

Captopril can increase potassium levels. Too much potassium can be dangerous. Potassium
supplements and potassium-sparing diuretics (amiloride, spironolactone, triamterene) can
increase the levels of potassium in your body. These drugs may be used with captopril, but only under your doctor’s supervision. Tell your doctor or pharmacist about any prescription or over-the-counter medicines or herbal products that you are taking. He or she can check for drug interactions.

If you miss a dose

If you miss a medicine dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose. Take your next dose at its scheduled time, and continue your usual dosing schedule. Do not “double up” on doses to catch up.

Avoid salt and salt substitutes

While you are on this medicine, you should avoid salt substitutes, because most contain potassium. You also should avoid having too much salt (sodium) in your diet. Do not stop taking this drug unless your doctor tells you to.

How to take this medicine

This medicine usually is taken 3 times a day, in the morning, afternoon, and evening. The tablets have lines down the center of them, so they can easily be broken to take half doses if that is what your doctor prescribed. Take this medicine exactly as your doctor prescribes. It’s best to take this medicine on an empty stomach (1 hour before meals).


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