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Georgios Zenonos, MD

Georgios Zenonos, MDAssistant Professor

Neurological Surgery

Associate Director

UPMC Center for Cranial Base Surgery

Areas of Interest


Dr. Zenonos became the associate director of the UPMC Center for Cranial Base Surgery in July 2019 after receiving extensive formal subspecialization in his field. He is one of a handful of board-certified neurosurgeons to have completed two fellowships in skull base surgery. At the University of Pittsburgh, one fellowship focused on endoscopic and minimally invasive approaches, and the other centered on complex open skull base approaches. His fellowship at the University of Miami was on complex cranial and cerebrovascular neurosurgery.

His specialized areas of interest include the following: endoscopic endonasal neurosurgery; minimally invasive neurosurgery; skull base tumors; Neuroendoport®brain surgery; skull base pathology; neuro-oncology; cerebrovascular neurosurgery; cranial nerve disorders; and radiosurgery. His research interests include: genetics of skull base tumors; surgical anatomy (refinement of skull base approaches, and surgical technique); skull base outcomes research; and high definition fiber tactography. Dr. Zenonos has published extensively and given numerous presentations nationally and internationally. He has been frequently invited as a scientific reviewer by prominent neurosurgical journals.

The goals of his clinical and research efforts are to always provide the best care possible to his patients, and to use the latest technologies and techniques, founded in evidence-based medicine.

Dr. Zenonos received his medical degree from National and Kapodistrian University of Athens School of Medicine in 2008. He completed his post-doctoral research fellowship at Harvard Medical School in 2010, followed by a minimally invasive and open skull base neurosurgery fellowship at the University of Pittsburgh in 2017. He then completed his neurological surgery residency at UPMC in 2018, followed in 2019 by a complex skull base and cerebrovascular neurosugery fellowship at the University of Miami.

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