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At UPMC, we're dedicated to developing new and effective therapies for sickle cell disease with the ultimate goal of finding a cure accessible to all.
Since the scientific community now has a greater understanding of the basic molecular processes and issues associated with sickle cell disease, we can devote many of our research efforts to clinical issues, such as specific treatment therapies, and developing gene-based therapeutics that will lead to a cure.
Experts at the UPMC Adult Sickle Cell Program conduct research studies across many interest areas in hopes of improving the lives of people with sickle cell disease.
Clinical research trials, typically just referred to as clinical trials, play a critical role in the advancement of medical knowledge.
By conducting clinical trials, we can:
| Who can participate | Both patients seen by the investigators and healthy volunteers, aged 18 or older. |
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| About the study | This study is designed to help develop new laboratory tests to help us study the genes your white blood cells are making, the proteins your white blood cells are making, and how well the cells that line your blood vessels (such as veins and arteries) are working. In order to do this, we are asking for donations of blood samples. This will help us develop better strategies of identifying specific diseases in blood. |
| Who to contact | Jude Jonassaint, RN — 412-623-1110 — to learn about eligibility requirements for this study. |
| Who can participate | Adults with sickle cell disease. |
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| About the study | This observational study investigates a new brain MRI protocol for detecting early evidence of accelerated brain aging and determining how these changes correlate with cognitive impairment in adult sickle cell patients. |
| Who to contact | Caterina Rosano, MD, MPH, Principal Investigator — RosanoC@edc.pitt.edu, 412-383-1294 — to learn about eligibility requirements. |
Learn more about pediatric sickle cell studies at UPMC Children's Hospital of Pittsburgh.
