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University Of Pittsburgh Researchers Receive $1 Million In Grants From Department Of Defense Breast Cancer Research Program

PITTSBURGH, November 15, 2004 The Department of Defense (DOD) Breast Cancer Research Program has announced that several researchers at the University of Pittsburgh are recipients of a total of more than $1 million in grants for breast cancer research. The awards, given to only 14 percent of grant applicants, will allow Pitt researchers to initiate six original projects on breast cancer prevention, detection and treatment.

Projects funded by the DOD grants include:

" Differential MDR Activity in Breast Cancer Stem Cells" by Albert Donnenberg, Ph.D., University of Pittsburgh Cancer Institute

" Design, Synthesis and Biological Evaluation of Focused Combinatorial Libraries of Antiestrogens" by Jelena M. Janjic, graduate student, University of Pittsburgh School of Pharmacy

" Statistical Modeling on Life Expectancy of Breast Cancer Patients" by Jong-Hyeon Jeong, M.D., department of biostatistics, Graduate School of Public Health

" Genetic Analysis of DNA Repair Deficiency in Novel Non-Tumor Adjacent and Tumor Cell Lines Suggests a New Paradigm of Breast Cancer Etiology" by Jean J. Latimer, Ph.D., Magee-Womens Research Institute

" Identification of Stem Cells in a Novel Human Mammary Epithelial Culture HMEC System that Reproducibly Demonstrates Ductal Organotypic Architecture in 3 Weeks" by Jean J. Latimer, Ph.D., Magee-Womens Research Institute

" An Organotypic Liver System for Tumor Progression" by Alan Wells, M.D., department of pathology, University of Pittsburgh School of Medicine

The DOD Breast Cancer Research Program was established in 1992 to provide funds for novel concepts in breast cancer. Throughout its history, more than 3,670 breast cancer projects have been selected for funding.

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