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Minimally Invasive Brain Surgery ​Legacy of Innovations

Like most medical and surgical breakthroughs, the development and expanded applications of the Endoscopic Endonasal Approach (EEA) and Neuroendoport® Surgery represent decades of dedicated study, research, and clinical application. UPMC remains at the forefront of minimally invasive brain surgery, and continues to attract surgical talent and research funding to further enhance these techniques.

Breakthroughs in Minimally Invasive Brain Surgery at UPMC


​1976 ​First craniofacial resection performed at UPMC
​1986 ​UPMC Center for Cranial Base Surgery established
​1994 ​First endoscopic pituitary surgery
​1999 ​First pediatric EEA (12-year-old child)
​2000 ​First EEA olfactory groove meningioma surgery
​2001 ​First endonasal infratemporal tumor surgery
​2001 ​First Neuroendoport surgery for ventricular tumor (colloid cyst)
​2002 ​EEA for the youngest patient ever (3-year-old child)
2003​ ​First Neuroendoport surgery for intraparenchymal tumor (in substance of the brain)
​2004 ​First endonasal odontoid resection
​2004 ​First EEA for a vascular malformation
​2005 ​First endonasal aneurysm surgery
​2005 ​UPMC hosts 1st World Congress for Endoscopic Surgery of the Brain, Skull Base, and Spine
​2008 ​1000th endoscopic endonasal surgery at UPMC
​2010 ​UPMC hosts 4th World Congress for Endoscopic Surgery of the Brain, Skull Base, and Spine

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