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Learn more about the centers and cores at the Pittsburgh Heart, Lung, Blood, and Vascular Medicine Institute and how our multidisciplinary team of scientists is advancing research in the heart, lung, and blood systems.

Heart and Vascular Clinical Trials

Clinical trials are research studies involving human volunteers who are closely monitored by:

  • Doctors
  • Nurses
  • Research assistants
  • Data analysts

If you are considering participation in a clinical trial, it is important to:

  • Discuss your health and review your medical records with your cardiologist and care team to determine eligibility.
  • Ask your cardiologist to assist you in discussing the decision with family members and caregivers, so questions or concerns can be addressed.
  • Work with your doctor to sign and consent to trial treatment.
  • Remember that participation is voluntary. You may choose to or be asked to cease participation in the trial at any time.

Learn more about the University of Pittsburgh's Research Participant Registry.

Search the US government's clinical trial database now for heart and vascular trials.

Featured Clinical Trials and Research

Evaluation of the GORE TAG Thoracic Branch Endoprosthesis of in the Treatment of
Proximal Descending Thoracic Aortic Aneurysms (SSB 11-02, investigational device)

Who can participate Patients with thoracic aortic aneurysms
What we'll study

The SSB 11-02 device treats thoracic aortic aneurysms, which generally occur in the elderly and can lead to a life-threatening rupture of the aorta, the largest artery in the body. Designed to seal-off a hard-to-treat section of the aorta, the device potentially provides a safe and less invasive alternative to open heart surgery.

Through thoracic branch technology and design, this device fits the unique characteristics of the descending aorta, allowing physicians to treat a subset of patients that could not be considered for total endovascular repair in the past.

Endovascular repair uses real-time x-ray and guidewires to help deliver a graft, inserted via catheter, to exclude the lesion inside the diseased aorta, making a new path for blood to flow. Through this less invasive technique, physicians can treat conditions through small incisions in the groin that might otherwise require open chest surgery.

It is hoped that the utilization of this device will reduce the need for invasive surgical procedures commonly required today, thus reducing the complications associated with treatment of this complex disease.

Who to contact To learn more about this study or about participating in future clinical trials, please contact the Division of Vascular Surgery by calling 1-855-UPMC-HVI (option 2) or email us at

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