View animation of EEA Technique


Meet Leslie

Leslie Snyder – Pituitary tumor patient story 

Leslie's blurry eyesight led to the discovery of a brain tumor. She was thankful to live in Pittsburgh and have easy access to the UPMC experts she knew she could trust.​

Read more »



Read More In Neurosurgery News

Learn how the Pituitary Center team leads telementoring for surgical techniques across the globe.
Read how EEA is a safe, effective approach for removing large pituitary tumors.



Pituitary and Skull Base Tumors and Disorders

World Leaders in Pituitary and Skull Base Tumor Treatment

At the UPMC Pituitary Center, we offer world-class care for pituitary and skull base tumors and lesions. Our surgeons' extensive experience with minimally invasive techniques attracts patients from around the world.

In addition to minimally invasive approaches, UPMC's neurosurgical team is trained and experienced in all traditional approaches to the brain, so they fully understand all of the options available to them. This expertise allows our neurosurgeons to develop the best treatment plan for you.

Conditions We Treat

UPMC is among the most experienced centers in the world in treating pituitary and skull base tumors using minimally invasive procedures, such as the Endoscopic Endonasal Approach (EEA) and Gamma Knife® Radiosurgery.

Common pituitary and skull base tumors and lesions we treat include:

View full list of pituitary/skull base tumors we treat »

Advanced Treatment Options at UPMC

At the UPMC Pituitary Center, our neurosurgeons have the depth and breadth of expertise required to treat pituitary and skull base tumors. Our team collaborates to seek the technique — or combination of techniques — that offers you the greatest opportunity for returning to normal life.

Depending on the patient's condition and location of the pituitary or skull base tumor, UPMC offers several preferred treatment options, including:

  • Endoscopic Endonasal Approach (EEA): Pioneered at UPMC, EEA is an innovative surgical technique used to remove brain tumors, pituitary tumors and lesions—some as large as softballs—all through the nose. EEA can offer benefits over open surgery such as:
    • Minimal scarring
    • Fewer side effects and complication
    • Faster recovery
  • ​​​​​Gamma Knife® Radiosurgery: A painless procedure that uses radiation beams to target tumors and lesions, with no surgical incision. Gamma Knife radiosurgery is especially useful when conventional surgical procedures pose a high risk for patients.
  • Endoscopic-Assisted Retromastoid Approach
  • Transorbital Approach​

Meet Our Experts in Pituitary and Skull Base Surgery

For more than 25 years, our multidisciplinary program has been treating patients with challenging pituitary and skull base tumors.

Read about our experts in pituitary and skull base surgery »

UPMC | Affiliated with the University of Pittsburgh Schools of the Health Sciences | Supplemental content provided by Healthwise, Incorporated. To learn more, visit

For help in finding a doctor or health service that suits your needs, call the UPMC Referral Service at 412-647-UPMC (8762) or 1-800-533-UPMC (8762). Select option 1.

UPMC is an equal opportunity employer. UPMC policy prohibits discrimination or harassment on the basis of race, color, religion, ancestry, national origin, age, sex, genetics, sexual orientation, gender identity, marital status, familial status, disability, veteran status, or any other legally protected group status. Further, UPMC will continue to support and promote equal employment opportunity, human dignity, and racial, ethnic, and cultural diversity. This policy applies to admissions, employment, and access to and treatment in UPMC programs and activities. This commitment is made by UPMC in accordance with federal, state, and/or local laws and regulations.

Medical information made available on is not intended to be used as a substitute for professional medical advice, diagnosis, or treatment. You should not rely entirely on this information for your health care needs. Ask your own doctor or health care provider any specific medical questions that you have. Further, is not a tool to be used in the case of an emergency. If an emergency arises, you should seek appropriate emergency medical services.

Pittsburgh, PA, USA |