Skip to Content
800-533-8762
  • Careers
  • Newsroom
  • Health Care Professionals
  • About Us
  • Contact Us
UPMC
  • Find a Doctor
  • Services
    • Frequently Searched Services
    • Frequently Searched Services
      Allergy & Immunology Behavioral & Mental Health Cancer Ear, Nose & Throat Endocrinology Gastroenterology Heart & Vascular Imaging Neurosciences Orthopaedics
      Physical Rehabilitation Plastic & Reconstructive Surgery Primary Care Senior Services Sports Medicine Telemedicine Transplant Surgery Walk-In Care Weight Management Women’s Health
      See all Services
    • Services by Region
    • Find a UPMC health care facility close to you quickly by browsing by region.
      UPMC in Western Pa. Western Pa. and New York
      UPMC in Central Pa. Central Pa.
      UPMC in North Central Pa. North Central Pa.
      UPMC in Western Md. Maryland & West Virginia
    • See All Services
  • Locations
    • Locations by Type
    • Locations by Type
      UPMC hospitals
      Hospitals
      Physical Therapy
      Physical Therapy
      Urgent care
      Walk-In Care
      UPMC Outpatient Centers
      Outpatient Centers
      UPMC Imaging Services
      Imaging
      Community Health Centers
      Community Health Centers
      See All Locations
    • Locations by Region
    • Locations by Region
      UPMC in Southwest Pa. Southwest Pa.
      UPMC in North Central Pa. North Central Pa.
      UPMC in Northwest Pa and Ny. Northwest Pa. & Western N.Y.
      UPMC in West Central Pa. West Central Pa.
      UPMC in Central Pa. Central Pa.
      UPMC in Western Md. Maryland & West Virginia
    • See All Locations
  • Patients & Visitors
    • Patient & Visitor Resources
    • Patient & Visitor Resources
      Patients and Visitors Resources Pay a Bill Classes & Events Medical Records Health Library Patient Information
      Patient Portals Privacy Information Shared Decision Making Traveling Patients Visitor Information
      Man uses mobile phone
      Pay a Bill
      Nurse reviews medical chart
      Request Medical Records
  • Patient Portals
  • Find Covid-19 updates
  • Schedule an appointment
  • Request medical records
  • Pay a bill
  • Learn about financial assistance
  • Find classes & events
  • Send a patient an eCard
  • Make a donation
  • Volunteer
  • Read HealthBeat blog
  • Explore UPMC Careers
Skip to Content
UPMC
  • Patient Portals
  • For Patients & Visitors
    • Find a Doctor
    • Locations
    • Patient & Visitor Resources
    • Pay a Bill
    • Services
    • More
      • Medical Records
      • Financial Assistance
      • Classes & Events
      • HealthBeat Blog
      • Health Library
  • About UPMC
    • Why UPMC
    • Facts & Stats
    • Supply Chain Management
    • Community Commitment
    • More
      • Financials
      • Support UPMC
      • UPMC Apps
      • UPMC Enterprises
      • UPMC International
  • For Health Care Professionals
    • Physician Information
    • Resources
    • Education & Training
    • Departments
    • Credentialing
  • Careers
  • Contact Us
  • Newsroom
  • UPMC >
  • Our Services >
  • Neurosurgery >
  • ... >
  • Brain >
  • Treatments >
  • Gamma Knife Radiosurgery
Neurosurgery
About Us
Contact Us
Conditions and Treatments
Brain
Conditions
Treatments
Endoscopic Endonasal Approach
Image Guided Neurosurgery
Transorbital Approach
Gamma Knife Radiosurgery
Neuroendoport Surgery
Microsurgery
Endovascular Surgery
Microvascular Decompression
Movement Disorders & Epilepsy Treatments
Brain Mapping
Spine Neurosurgery
Neurophysiology
Meet the Neurosurgery Experts
Patient Stories
Classes, Events, & News
Neurocirugia
Neurosurgery
About Us
Contact Us
Conditions and Treatments
Brain
Conditions
Treatments
Endoscopic Endonasal Approach
Image Guided Neurosurgery
Transorbital Approach
Gamma Knife Radiosurgery
Neuroendoport Surgery
Microsurgery
Endovascular Surgery
Microvascular Decompression
Movement Disorders & Epilepsy Treatments
Brain Mapping
Spine Neurosurgery
Neurophysiology
Meet the Neurosurgery Experts
Patient Stories
Classes, Events, & News
Neurocirugia

Chat Keywords List

  • cancel or exit: Stops your conversation
  • start over: Restarts your current scenario
  • help: Shows what this bot can do
  • terms: Shows terms of use and privacy statement
  • feedback: Give us feedback
Continue
Chat with UPMC
RESTART
MENU
CLOSE
Gamma Knife Radiosurgery - Desktop Banner
Gamma Knife Radiosurgery - Mobile Banner

Gamma Knife® Radiosurgery at UPMC

If you have a tumor or other anomaly in your brain, your doctor may suggest Gamma Knife® radiosurgery.

Despite its name, a Gamma Knife procedure isn't surgery.

Rather, it's a painless treatment that uses radiation beams to target tumors and lesions. There are no incisions or stitches in Gamma Knife treatment.

Contact the UPMC Department of Neurosurgery

To make an appointment or learn more:

  • Call us at 1-412-647-3685 or outside the U.S., call 1-877-320-8762.
  • Fill out our UPMC Neurosurgery contact form.

What Is Gamma Knife Radiosurgery?

Gamma Knife radiosurgery is a non-invasive and highly precise radiation treatment for brain tumors and other issues.

Highly focused gamma rays target the affected part of the brain while lessening exposure to surrounding healthy tissue.

What Is the Gamma Knife Used For?

Our experts in Gamma Knife radiosurgery at UPMC can treat an array of brain disorders.

The results after Gamma Knife treatment differ based on the type of tumor:

Treatment can reduce the size or limit the growth of the tumor with little risk of lasting nerve damage.

Learn more about acoustic neuroma.

Blood vessels in the AVM thicken and close.

Learn more about AVM.

 Treatment damages the genetic material in the tumor's cells so they're no longer able to reproduce. The cells die and the tumor may gradually shrink.

Learn more about brain tumors.

Treatment can shrink the tumor and lessen the disruption of the pituitary hormones.

Learn more about pituitary and skull base tumors.

Treatment alters the nerve fibers that cause intense face pain.

Learn more about trigeminal neuralgia.

How Should I Prep for My Gamma Knife Radiosurgery?

You need to stop eating and drinking by midnight the night before your Gamma Knife treatment.

Ask your neurosurgeon about any prescription drugs you take. They'll tell you what medicines you can and can't take that day.

The day of your treatment:

  • Wear comfy clothes.
  • Skip hair products like spray or gel. Your doctor may give you special shampoo to wash your hair with.
  • Don't wear jewelry, hair pieces, makeup, or nail polish.
  • Remove contacts, glasses, and dentures.
  • Bring a loved one who can drive you home.

Prepping you for your Gamma Knife surgery

Before the treatment begins, doctors will:

  • Fit you with a circular frame to put your head in the right place.
  • Attach this metal frame to your scalp and skull with small pins. You'll get numbing shots, so you won't feel pain from the pins.
  • Take pictures of your brain using either CT scans, MRIs, or angiograms. The images will show the exact location, size, and shape of the tumor or other problem area.

What Happens During Gamma Knife Radiosurgery?

The Gamma Knife treatment takes between 20 minutes and several hours. You'll have an IV with medicine to help you relax, but you'll be awake the whole time.

The treatment itself is painless.

Here's what happens during Gamma Knife radiosurgery:

  • You'll lie on a table. Doctors will fit a special helmet over the head frame. The helmet has tiny holes that allow precise beams of radiation to pass through.
  • The table slides into a machine that delivers the radiation.
  • Your head frame and helmet will line up with the machine and click into place.
  • Your care team will go to another room. You can talk to them through an intercom. They'll watch you on cameras.
  • The Gamma Knife® unit will deliver the radiation. You won't feel anything while this happens.
  • The radiation targets the diseased tissue. It leaves healthy tissue around it intact.

What Happens After Gamma Knife Radiosurgery?

Once the treatment is over, doctors will watch you to make sure you recover well. You can eat and drink as soon as you're able.

You may be able to go home the same day as your treatment. You'll need someone to drive you, as the medicine you get can make you sleepy.

If your doctor says it's OK, you can go back to your normal routine the next day.

You may need just one Gamma Knife treatment. Or, based on your health issue, you may need more sessions. Your doctor will give you more details.

What Are the Side Effects of Gamma Knife Surgery?

The side effects from Gamma Knife surgery are typically less than those from standard brain surgery.

Gamma Knife radiation is less likely to damage the healthy tissue around the treated area.

But as with any health treatment, there are risks.

Gamma Knife® side effects may include:

  • Fatigue.
  • Headache.
  • Nausea and vomiting.
  • Swelling in the treated area.
  • Tenderness and bruising where the head frame attached to your scalp.

Life expectancy after Gamma Knife® surgery depends on your health problem.

Your doctor will want to see you for follow-up tests like MRIs and CT scans. They'll be able to tell you more about your prognosis.

What Is the Success Rate of Gamma Knife Surgery?

Over its 30-year history at UPMC, Gamma Knife radiosurgery has proved effective for more than 18,000 people with:

  • Benign or malignant brain tumors.
  • Vascular malformations.
  • Pain.
  • Other functional problems.

Pioneers in Gamma Knife treatment

UPMC installed the first North American Gamma Knife in 1987. Since then, we've introduced and pioneered technological improvements.

Today, the Center for Image-Guided Neurosurgery at UPMC leads the nation in Gamma Knife treatments. It's also a major teaching center for neurosurgeons, radiation oncologists, and health physicists from around the globe.

Leaders in using the latest Gamma Knife models

UPMC is one of the first in the U.S. to use the Gamma Knife Icon™. This is the most advanced model of Gamma Knife radiosurgery.

The GK Icon's cutting-edge technology:

  • Allows for a frame-based or frameless approach to radiosurgery, giving surgeons more options when treating complex brain issues.
  • Uses radiological images to target areas in the brain more precisely than ever before.
  • Offers dosage control and motion management systems to administer treatment with extreme accuracy.

Medical Mondays

UPMC Health Beat

Follow the beat for a healthier life. Read our blog posts:

  • Recovery After Gamma Knife Radiosurgery
  • What Conditions Does Gamma Knife Radiosurgery Treat?
  • What is Gamma Knife Radiosurgery?

 

 

Aneurysm AVM Support Group 

Join us at an upcoming Aneurysm-AVM Support Group meeting.

View meeting location and dates


Quick Links

  • Patient Stories
  • For Pediatric Patients
  • Legacy of Innovation

Neurosurgery News 

Read the Gamma Knife Radiosurgery Issue of Neurosurgery News

 
 

Meet John

John Lynch – Arteriovenous Malformation patient story 

When John Lynch was diagnosed with a potentially fatal brain disorder 25 years ago, he turned to groundbreaking Gamma Knife Radiosurgery at UPMC.

Read more »

 
UPMC
200 Lothrop Street Pittsburgh, PA 15213

412-647-8762 800-533-8762

Patients And Visitors
  • Find a Doctor
  • Locations
  • Pay a Bill
  • Patient & Visitor Resources
  • Disabilities Resource Center
  • Services
  • Medical Records
  • No Surprises Act
  • Price Transparency
  • Financial Assistance
  • Classes & Events
  • Health Library
Health Care Professionals
  • Physician Information
  • Resources
  • Education & Training
  • Departments
  • Credentialing
Newsroom
  • Newsroom Home
  • Inside Life Changing Medicine Blog
  • News Releases
About
  • Why UPMC
  • Facts & Stats
  • Supply Chain Management
  • Community Commitment
  • Financials
  • Supporting UPMC
  • HealthBeat Blog
  • UPMC Apps
  • UPMC Enterprises
  • UPMC Health Plan
  • UPMC International
  • Nondiscrimination Policy
Life changing is...
Follow UPMC
  • Contact Us
  • Website/Email Terms of Use
  • Medical Advice Disclaimer
  • Privacy Information
  • Active Privacy Alerts
  • Sitemap
© 2025 UPMC I Affiliated with the University of Pittsburgh Schools of the Health Sciences Supplemental content provided by Healthwise, Incorporated. To learn more, visit healthwise.org
Find Care
Providers
Video Visit
Portal Login