Find a Doctor
Browse UPMC doctors and medical professionals to find the care that's right for you. Customize your search by specialty, zip code, last name, and more.
Visit the UPMC Find a Doctor website.
Talimogene laherparepvec is a live, weakened type 1 herpes simplex virus used to treat cancer. It is given into your skin cancer.
These symptoms may happen within a few hours after your treatment and may last up to 24 hours. Medicines are available to stop or lessen these side effects.
Avoid touching or scratching the site where you get your shot or coverings to your shot site. This could lead to spreading of the virus to other parts of your body.
Caregivers and patients should wear gloves when changing dressings to avoid spreading the virus to other parts of the body. Caregivers or healthcare providers who have a weakened immune system or are pregnant should not come into direct contact with a patient’s shot site, dressings that covered the shot site, or body fluids of this patient.
Your skin cancer and shot site should stay covered for 7 days. Dirty dressings should be properly disposed.
There are no known interactions of talimogene laherparepvec with food.
This drug may interact with other medications such as acyclovir. Tell your doctor and pharmacist about all the medication and dietary supplements (vitamins, minerals, herbs, and others) that you are currently taking. The safety and effectiveness of dietary supplements and alternative diets are often unknown. Using these might unexpectedly affect your cancer or interfere with your treatment. Until more is known, you should not use dietary supplements or alternative diets without your cancer doctor's advice.
Call your doctor or nurse immediately if you have any of the following symptoms:
Call your doctor or nurse as soon as possible if any of the following symptoms occur:
This drug may cause very harmful effects on an unborn child. Talimogene laherparepvec should never be used by women who are pregnant or who could become pregnant while taking the drug. Even 1 dose taken by a pregnant woman can cause these very harmful effects. Your healthcare team will talk to you and give you written information about this risk.
It is not known if this drug passes into breast milk. For this reason, women should talk to their doctor about the risks and benefits of breast feeding during treatment with this drug because this drug may enter the breast milk and badly harm a breast feeding baby.