Also part of the UPMC family:
Also part of the UPMC family:

John W. Mellors, MD

Dr. Mellors is interested in antiviral therapy of HIV infection and AIDS. This includes the evaluation of new antiretroviral compounds, both in the laboratory and in clinical trials, and studies on the mechanisms of antiviral drug resistance. An important obstacle to effective long-term treatment of patients with HIV infection, drug-resistance has developed to most antiretrovirals and is largely responsible for resurgent viremia, clinical deterioration and death despite continued therapy. Effective strategies are needed to prevent the emergence of drug-resistant HIV and to treat patients in whom drug-resistant virus is present.

The primary focus of Dr. Mellors' research is to detect and characterize viral variants that are resistant to antiretroviral drugs. This line of research can elucidate the mechanisms of drug action and drug resistance, identify alternative drug therapies for resistant virus, and help devise strategies to prevent the development of drug resistance. Dr. Mellors' other research interests include clinical trials of new antiretroviral drug combinations, studies of viral load as a predictor of disease outcome, and salvage treatment regimens.

Find a Doctor

Browse UPMC doctors and medical professionals to find the care that's right for you. Customize your search by specialty, zip code, last name, and more.


Visit the UPMC Find a Doctor website.
Make an Appointment

Find important information on scheduling your appointment or finding a doctor or service that meets your needs.


Request an appointment now.
Find a Location

Browse addresses and contact information for our network of hospitals, specialty care practices, and community health locations.


Find a UPMC location near you.
Pay Your Bill

Learn more about how to pay your UPMC bill. Find resources including payment methods and contact information for assistance.


Pay your bill now.
Find a Job

Advance your career with UPMC. Discover our latest job listings and learn about our values and career pathways.


Find your ideal job at UPMC.