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  • Adventitial Cystic Disease

Adventitial Cystic Disease

Adventitial cystic disease is a rare vascular condition characterized by the formation of a cyst within the outer layer of an artery.

Looking for Adventitial Cystic Disease Care?

Related services:
  • Heart and Vascular.
  • Primary Care.
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On this page:

  • What Is Adventitial Cystic Disease?
  • What Are the Signs and Symptoms of Adventitial Cystic Disease?
  • How Do You Diagnose Adventitial Cystic Disease?
  • How Do You Treat Adventitial Cystic Disease?

What Is Adventitial Cystic Disease?

With adventitial cystic disease, a cyst made of a mucous-like substance forms in an artery. This limits or blocks blood flow.

The condition is most common in the popliteal artery, which supplies blood to the:

  • Calf muscles
  • Feet
  • Knee joints

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What Are the Signs and Symptoms of Adventitial Cystic Disease?

If you have adventitial cystic disease, you may feel:

  • Pain or heaviness in your legs or behind the knee especially when you walk or exercise.
  • Cramps in the legs.

In most cases, the pain will slowly go away when you stop moving.

For most people, symptoms of adventitial cystic disease go away after a few weeks or months.

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How Do You Diagnose Adventitial Cystic Disease?

To diagnose adventitial cystic disease, your UPMC vascular surgeon will:

  • Give you a thorough physical exam.
  • Check the pulse in your foot and popliteal artery.
  • Order imaging tests.

Tests that can confirm the location and size of the cyst include:

  • Ultrasound — a type of scan that uses sound waves to image the artery and measure blood flow.
  • Computed tomographic angiography (CTA) — a type of CT scan that shows areas around the knee with poor blood flow or narrowed arteries.
  • Magnetic resonance angiography (MRA) — an imaging test that uses magnetic fields and radio waves to check soft tissue within the body.

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How Do You Treat Adventitial Cystic Disease?

Treatment for adventitial cystic disease often includes surgery.

Your surgeon will remove the cyst and/or replace the section of the blood vessel where the cyst formed.

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By UPMC Editorial Team. Reviewed on 2025-02-27.

2024-10-01
2026-02-20
Adventitial Cystic Disease
Adventitial cystic disease is a cyst that forms & blocks blood flow.
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