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Dr. Gold’s research focuses on the design, synthesis and characterization of molecules that sequence-specifically bind to duplex DNA via triple helix formation in order to modulate gene transcription; the generation of anticancer drugs that efficiently form DNA lesions that are deadly to the cell but do not cause mutations that could lead to secondary cancers; and the development of small-molecule inhibitors of specific DNA repair pathways that are involved in tumor resistance to anticancer drugs.
He has published more than 100 peer-reviewed articles and has been the lead inventor on three patents. He has maintained continuous National Institutes of Health funding since 1977 and has appeared in the Chicago Tribune.
Dr. Gold earned his doctorate in 1971 from the University of Nebraska-Lincoln.