Also part of the UPMC family:
Also part of the UPMC family:

Garson David Roodman, MD, PhD

At UPCI, Dr. Roodman focuses his research on the investigation of multiple myeloma, a cancer of the plasma cells that play a vital role in the body's immune defenses. In addition to multiple myeloma, Dr. Roodman's research focuses on Paget's disease of the bone, the second most common bone disease diagnosed in the United States.

Dr. Roodman is studying the mechanisms that control and promote osteoclast formation to limit the breakdown of bone tissue that occurs in both diseases. In patients with multiple myeloma and Paget's disease, osteoclast activity is increased, resulting in the destruction of bone.

Prior to his position at UPCI, Dr. Roodman was associate chair for research in the department of medicine at the University of Texas Health Science Center in San Antonio. While there, he identified an enzyme, OIP-2, that appears to be a regulator of osteoclast formation. OIP-2 may be responsible for restricting osteoclast numbers to low levels, and thus holds promise as a treatment for patients with multiple myeloma and Paget's disease suffering from damaged and weakened bones. Dr. Roodman also is examining MIP1-alpha receptor antagonists to determine their promise as a therapeutic agent for patients with multiple myeloma.

Dr. Roodman has authored and co-authored more than 150 publications in the medical literature. He is a member of the American Society of Hematology, International Society for Experimental Hematology and the American Society for Bone and Mineral Research, among others. He is on the editorial board of several journals including the Journal of Clinical Investigation and Experimental Hematology

Find a Doctor

Browse UPMC doctors and medical professionals to find the care that's right for you. Customize your search by specialty, zip code, last name, and more.

Visit the UPMC Find a Doctor website.
Make an Appointment

Find important information on scheduling your appointment or finding a doctor or service that meets your needs.

Request an appointment now.
Find a Location

Browse addresses and contact information for our network of hospitals, specialty care practices, and community health locations.

Find a UPMC location near you.
Pay Your Bill

Learn more about how to pay your UPMC bill. Find resources including payment methods and contact information for assistance.

Pay your bill now.
Find a Career

Advance your career with UPMC. Discover our latest job listings and learn about our values and career pathways.

Find your ideal career at UPMC.