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  • Infective Endocarditis

Infective Endocarditis

Endocarditis is a bacterial infection in the bloodstream.

When left untreated, infective endocarditis can be life-threatening, damaging your heart or destroying your heart valves.

Looking for Infective Endocarditis Care?

Related services:
  • Heart and Vascular.
  • Primary Care.
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On this page:

  • What Is Endocarditis?
  • What Are the Signs and Symptoms of Infective Endocarditis?
  • How Do You Diagnose Infective Endocarditis?
  • How Do You Treat Infective Endocarditis?

What Is Endocarditis?

Endocarditis is an infection caused by bacteria in the bloodstream. The bacteria settle in your heart's inner lining or a heart valve, causing an infection.

The bacteria can enter your body:

  • Through injection drug use.
  • Through central venous access lines.
  • During dental or surgical procedures.

Fungi, or other germs from your body that spread to your heart through your bloodstream, can also cause it.

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Infective endocarditis risk factors

People are at higher risk of infective endocarditis if they have certain heart problems, including:

  • An artificial heart valve.
  • A prior endocarditis infection
  • Certain birth defects of the heart.
  • A damaged or abnormal heart valve.

People at higher risk of getting endocarditis may receive antibiotics before some dental procedures.

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Complications of infective endocarditis

When left untreated, infective endocarditis can damage or even destroy your heart valves. This can be life-threatening.

Stroke is also possible if parts of the infection break off and cause blood clots.

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What Are the Signs and Symptoms of Infective Endocarditis?

Endocarditis has symptoms like other infections, including

  • Fever
  • Chills
  • Sweating

Infective endocarditis symptoms may progress slowly or come on suddenly. Sometimes symptoms come and go.

Other signs and symptoms of infective endocarditis include:

  • Fatigue or weakness.
  • Aches.
  • A new or changed heart murmur.
  • Areas of bleeding under the nails.
  • Red skin spots on your palms and the soles of your feet that aren't painful.
  • Shortness of breath.
  • Swelling of your feet, legs, or stomach.

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How Do You Diagnose Infective Endocarditis?

You should see a doctor right away if you have any symptoms of endocarditis.

Your doctor will review your signs and symptoms and might order tests to confirm a diagnosis of infective endocarditis.

Tests you might have include:

  • Blood tests — to look for the type of bacteria present or signs of the infection.
  • Echocardiogram — to see your heart's structure and look for damage, or to check the heart valves for damage or infection.
  • Chest x-ray — to see if the infection has enlarged your heart or spread to your lungs.

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How Do You Treat Infective Endocarditis?

Treatment for infective endocarditis begins with an IV of antibiotics in the hospital.

After leaving the hospital, most people need long-term antibiotics — about four to six weeks — to kill all the harmful bacteria.

In some cases, you may need surgery to replace the infected heart valve if:

  • The infection causes stroke.
  • You develop heart failure.
  • There are signs of severe organ damage.

Getting treatment right away gives you the best chance for treating the infection.

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By UPMC Editorial Team. Reviewed on 2025-02-27.

2024-10-01
2026-02-20
Infective Endocarditis
Infective endocarditis is a potentially fatal inflammation of your heart valves' lining.
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