Skip to Content
800-533-8762
  • Careers
  • Newsroom
  • Health Care Professionals
  • About Us
  • Contact Us
UPMC
  • Find a Doctor
  • Services
    • Frequently Searched Services
    • Frequently Searched Services
      Allergy & Immunology Behavioral & Mental Health Cancer Ear, Nose & Throat Endocrinology Gastroenterology Heart & Vascular Imaging Neurosciences Orthopaedics
      Physical Rehabilitation Plastic & Reconstructive Surgery Primary Care Senior Services Sports Medicine Telemedicine Transplant Surgery Walk-In Care Weight Management Women’s Health
      See all Services
    • Services by Region
    • Find a UPMC health care facility close to you quickly by browsing by region.
      UPMC in Western Pa. Western Pa. and New York
      UPMC in Central Pa. Central Pa.
      UPMC in North Central Pa. North Central Pa.
      UPMC in Western Md. Maryland & West Virginia
    • See All Services
  • Locations
    • Locations by Type
    • Locations by Type
      UPMC hospitals
      Hospitals
      Physical Therapy
      Physical Therapy
      Urgent care
      Walk-In Care
      UPMC Outpatient Centers
      Outpatient Centers
      UPMC Imaging Services
      Imaging
      Community Health Centers
      Community Health Centers
      See All Locations
    • Locations by Region
    • Locations by Region
      UPMC in Southwest Pa. Southwest Pa.
      UPMC in North Central Pa. North Central Pa.
      UPMC in Northwest Pa and Ny. Northwest Pa. & Western N.Y.
      UPMC in West Central Pa. West Central Pa.
      UPMC in Central Pa. Central Pa.
      UPMC in Western Md. Maryland & West Virginia
    • See All Locations
  • Patients & Visitors
    • Patient & Visitor Resources
    • Patient & Visitor Resources
      Patients and Visitors Resources Pay a Bill Classes & Events Medical Records Health Library Patient Information
      Patient Portals Privacy Information Shared Decision Making Traveling Patients Visitor Information
      Man uses mobile phone
      Pay a Bill
      Nurse reviews medical chart
      Request Medical Records
  • Patient Portals
  • Find Covid-19 updates
  • Schedule an appointment
  • Request medical records
  • Pay a bill
  • Learn about financial assistance
  • Find classes & events
  • Send a patient an eCard
  • Make a donation
  • Volunteer
  • Read HealthBeat blog
  • Explore UPMC Careers
Skip to Content
UPMC
  • Patient Portals
  • For Patients & Visitors
    • Find a Doctor
    • Locations
    • Patient & Visitor Resources
    • Pay a Bill
    • Services
    • More
      • Medical Records
      • Financial Assistance
      • Classes & Events
      • HealthBeat Blog
      • Health Library
  • About UPMC
    • Why UPMC
    • Facts & Stats
    • Supply Chain Management
    • Community Commitment
    • More
      • Financials
      • Support UPMC
      • UPMC Apps
      • UPMC Enterprises
      • UPMC International
  • For Health Care Professionals
    • Physician Information
    • Resources
    • Education & Training
    • Departments
    • Credentialing
  • Careers
  • Contact Us
  • Newsroom
  • UPMC >
  • Our Services >
  • Heart & Vascular >
  • Conditions We Treat >
  • Vasculitis
Heart & Vascular
About Us
Conditions We Treat
Abdominal Aortic Aneurysm
Adult Congenital Heart Disease
Adventitial Cystic Disease
Aneurysms
Angina
Aortic Coarctation
Aortic Disease
Aortic Dissection
Aortic Root Aneurysm
Aortic Stenosis
Aortoiliac Occlusive Disease
Aortopathy
Arrhythmia
Arrhythmogenic Right Ventricular Cardiomyopathy
Arteriovenous Malformation
Ascending Aortic Arch Aneurysm
Atherosclerosis
Atrial Fibrillation
AV Fistula
Bicuspid Aortic Valve
Brachiocephalic Arterial Insufficiency
Bradycardia
Brugada Syndrome
Buergers Disease
Cardiac Amyloidosis
Cardiac Arrest
Cardiomyopathy
Carotid Artery Disease
Carotid Artery Stenosis
Chronic Coronary Total Occlusion
Chronic Mesenteric Ischemia
Chronic Venous Insufficiency
Connective Tissue Disorder
Coronary Artery Disease
Coronary Vasospasm
Deep Vein Thrombosis
Diabetic Arterial Disease
Dilated Cardiomyopathy
Dysphagia Lusoria
Familial Lipid Syndrome
Fibromuscular Dysplasia
Foot Leg Ulcers
Gestational Hypertension
Giant Cell Arteritis
Heart Disease
Heart Failure
Heart Murmurs
Heart Palpitations
Heart Valve Disease
Hypercholesterolemia
Hyperlipidemia
Hypertrophic Cardiomyopathy
Infective Endocarditis
Left Ventricular Cardiomyopathy
Long QT Syndrome
Lyme Carditis
Lymphedema
Marfan Syndrome
May Thurner Syndrome
Mitral Valve Disease
Mitral Valve Regurgitation
Mitral Valve Stenosis
Myocarditis
Nutcracker Syndrome
Pediatric Congenital Heart Disease
Pericarditis
Peripartum Cardiomyopathy
Peripheral Aneurysm
Peripheral Artery Disease
Peripheral Venous Disease
Popliteal Artery Entrapment Syndrome
Postpartum Hypertension
Postural Orthostatic Tachycardia Syndrome
Premature Ventricular Contraction
Pulmonary Embolism
Spontaneous Coronary Artery Dissection
Tachycardia
Thoracic Aortic Aneurysm
Thoracic Outlet Syndrome
Varicose Spider Veins
Vascular Malformations
Vascular Trauma
Vasculitis
Vasospastic Disorder
Venous Thromboembolism
Venous Ulcer
Visceral Artery Aneurysm
Wolff Parkinson White Syndrome
Our Services
For Patients
For Professionals & Students
Our Locations
Contact Us
Heart & Vascular
About Us
Conditions We Treat
Abdominal Aortic Aneurysm
Adult Congenital Heart Disease
Adventitial Cystic Disease
Aneurysms
Angina
Aortic Coarctation
Aortic Disease
Aortic Dissection
Aortic Root Aneurysm
Aortic Stenosis
Aortoiliac Occlusive Disease
Aortopathy
Arrhythmia
Arrhythmogenic Right Ventricular Cardiomyopathy
Arteriovenous Malformation
Ascending Aortic Arch Aneurysm
Atherosclerosis
Atrial Fibrillation
AV Fistula
Bicuspid Aortic Valve
Brachiocephalic Arterial Insufficiency
Bradycardia
Brugada Syndrome
Buergers Disease
Cardiac Amyloidosis
Cardiac Arrest
Cardiomyopathy
Carotid Artery Disease
Carotid Artery Stenosis
Chronic Coronary Total Occlusion
Chronic Mesenteric Ischemia
Chronic Venous Insufficiency
Connective Tissue Disorder
Coronary Artery Disease
Coronary Vasospasm
Deep Vein Thrombosis
Diabetic Arterial Disease
Dilated Cardiomyopathy
Dysphagia Lusoria
Familial Lipid Syndrome
Fibromuscular Dysplasia
Foot Leg Ulcers
Gestational Hypertension
Giant Cell Arteritis
Heart Disease
Heart Failure
Heart Murmurs
Heart Palpitations
Heart Valve Disease
Hypercholesterolemia
Hyperlipidemia
Hypertrophic Cardiomyopathy
Infective Endocarditis
Left Ventricular Cardiomyopathy
Long QT Syndrome
Lyme Carditis
Lymphedema
Marfan Syndrome
May Thurner Syndrome
Mitral Valve Disease
Mitral Valve Regurgitation
Mitral Valve Stenosis
Myocarditis
Nutcracker Syndrome
Pediatric Congenital Heart Disease
Pericarditis
Peripartum Cardiomyopathy
Peripheral Aneurysm
Peripheral Artery Disease
Peripheral Venous Disease
Popliteal Artery Entrapment Syndrome
Postpartum Hypertension
Postural Orthostatic Tachycardia Syndrome
Premature Ventricular Contraction
Pulmonary Embolism
Spontaneous Coronary Artery Dissection
Tachycardia
Thoracic Aortic Aneurysm
Thoracic Outlet Syndrome
Varicose Spider Veins
Vascular Malformations
Vascular Trauma
Vasculitis
Vasospastic Disorder
Venous Thromboembolism
Venous Ulcer
Visceral Artery Aneurysm
Wolff Parkinson White Syndrome
Our Services
For Patients
For Professionals & Students
Our Locations
Contact Us

Chat Keywords List

  • cancel or exit: Stops your conversation
  • start over: Restarts your current scenario
  • help: Shows what this bot can do
  • terms: Shows terms of use and privacy statement
  • feedback: Give us feedback
Continue
Chat with UPMC
RESTART
MENU
CLOSE

Vasculitis

Vasculitis refers to a group of conditions that cause inflammation in the blood vessels.

At UPMC, we collaborate with experts from many disciplines to diagnose and treat vasculitis. The specialists we work with include joint and muscle, infectious disease, skin, lung, kidney, nervous system, heart, eye, and urinary tract experts.

Looking For Vasculitis Care?

Related services:

  • Heart and Vascular

Find a Provider

On this page

  • What Is Vasculitis?
  • What Are The Symptoms Of Vasculitis?
  • How Do You Diagnose Vasculitis?
  • How Do You Treat Vasculitis?

What Is Vasculitis?

Vasculitis is a group of conditions that causes inflammation in the blood vessels.

It can be:

  • Systemic, affecting multiple systems in the body.
  • Isolated to a specific blood vessel group.

Vasculitis is complex and can range from mild to life threatening.

It may happen once in a person’s life and never recur. In some cases, vasculitis can recur after successful treatment.

Some people need lifelong treatment for vasculitis.

What are the types of vasculitis?

There are many types of vasculitis.

Behçet's disease

  • Causes ulcers in the mouth and genitals, skin lesions, and eye inflammation.
  • Usually affects people age 20-40. Men are more likely to have it than women.

Buerger’s disease (tormboangiits obliterans)

  • Buerger’s disease causes swelling and blood clots in the small and medium-sized arteries in the hands and feet. This leads to pain, discoloration, and skin ulcers.
  • Linked to tobacco use.

Cogan’s syndrome

  • Mainly affects the aorta and aortic valve in people with systemic vasculitis.
  • Can cause eye inflammation, hearing changes, and deafness.

Cryoglobulinemia vasculitis

  • Can cause symptoms like rash, joint pain, weakness, and tingling or numbness.
  • Usually associated with hepatitis C.

Eosinophilic granulomatosis with polyangiitis (Churg-Strauss syndrome)

  • Very rare type of vasculitis.
  • Can affect the lungs, skin, kidneys, nervous system, and heart with varied symptoms.

Giant cell arteritis

  • Giant cell arteritis causes inflammation in the arteries of the scalp and head, but can affect any artery.
  • Common symptoms include headache, jaw pain, and vision problems.
  • Mostly affects people age 50 and older.

Hypersensitivity vasculitis

  • Can cause red spots on the skin, mainly in the lower legs.
  • Usually associated with a reaction to medicine or an infection.

IgA vasculitis (Henoch-Schonlein purpura)

  • Can cause rash, abdominal pain, swollen and painful joints, and blood in urine.
  • Most common in children between 2 and 11 years old.
  • Often follows a respiratory, throat, or gastrointestinal infection.

Kawasaki disease (mucocutaneous lymph node syndrome)

  • Rare condition that affects children.
  • Causes fever, rash, and eye inflammation.

Microscopic polyangiitis

  • Usually affects the kidneys and lungs.
  • Can cause fever, weight loss, and muscle aches.

Polyarteritis nodosa

  • Can cause fever, general malaise, weight loss, muscle and joint aches, anemia, rash and other skin changes, and stomach pain after eating.
  • Often associated with hepatitis B.

Polymyalgia rheumatica

  • Affects the shoulders and hips, causing pain and stiffness.
  • Often associated with giant cell arteritis.

Takayasu’s arteritis

  • Causes inflammation in the aorta and its branches, and in the arteries of the arms, brain, and abdominal organs.
  • Can cause stroke in severe cases.

What causes vasculitis?

Vasculitis happens when your immune system attacks your blood vessels by mistake.

What are vasculitis risk factors and complications?

While doctors don't know exactly why this happens, some risk factors can include:

  • Autoimmune disorders like lupus, rheumatoid arthritis, and scleroderma.
  • Medicines.
  • Infections like hepatitis B, hepatitis C, or viral illness.
  • Blood cancers.

Complications of vasculitis

Vasculitis can damage blood vessels, causing them to become thick, weak, narrow, or scarred. This can limit blood flow, keeping your organs and tissues from getting the oxygen and nutrients they need.

Complications from vasculitis can include:

  • Organ damage.
  • Blood clots.
  • Aneurysm, or a bulge or weak spot in a blood vessel.
  • Vision loss or blindness.
  • Infections like pneumonia and sepsis (blood infection).
  • Limb loss.

Back to top


What Are The Signs And Symptoms Of Vasculitis?

Symptoms of vasculitis can vary greatly, but often include:

  • Fever.
  • Aches and pains, including headaches.
  • Rash.
  • Fatigue.
  • Shortness of breath or cough.
  • Numbness or pain in a hand or foot.

Depending on what organs or body systems it affects, other vasculitis symptoms can include:

  • Mouth ulcers.
  • Itching.
  • Stomach pain.
  • Sinus or inner ear infections.
  • Eye itching or burning.
  • Trouble thinking clearly.
  • Stroke-like symptoms, including muscle weakness.

Back to top


How Do You Diagnose Vasculitis?

To diagnose vasculitis, your surgeon will ask about your medical history and symptoms.

He or she will perform a physical exam and may use the following tests to confirm your diagnosis:

  • Blood tests to check for inflammation.
  • A biopsy of a blood vessel to confirm inflammation.
  • Imaging tests like an x-ray, CT scan, or MRI.

Back to top


How Do You Treat Vasculitis?

The main goal of vasculitis treatment is to reduce and control the inflammation in your blood vessels.

Treatment options include:

  • Medicines like steroids and immunosuppressant drugs.
  • Blood thinners.
  • Plasmapheresis, a process that filters certain proteins from your blood.
  • Angioplasty, a catheter-based procedure that uses a balloon to open blocked blood vessels.
  • Bypass surgery to restore blood flow.

In some cases, your vascular surgeon may successfully treat your vasculitis, but then it returns.

Some people need ongoing treatment for the rest of their lives.

Living with vasculitis

Vasculitis can require short-term or lifelong treatment, depending on your condition and symptoms.

Some people who need ongoing treatment can experience:

Side effects from medication.

  • Fear.
  • Anxiety.
  • Depression.
  • Stress.

Vasculitis management

To help manage your vasculitis:

  • Stay on your treatment plan and talk with your doctor about any medication side effects. Your doctor may be able to adjust the dose to help reduce side effects.
  • Quit or avoid smoking.
  • Choose healthy foods to help control your risk factors for vascular disease, like your blood pressure, cholesterol, and blood sugar levels.
  • Get and stay active. Regular physical activity can help lower your risk for high blood pressure and diabetes. It can also help you manage stress.

By UPMC Editorial Staff. Last reviewed on 2024-10-01.

UPMC
200 Lothrop Street Pittsburgh, PA 15213

412-647-8762 800-533-8762

Patients And Visitors
  • Find a Doctor
  • Locations
  • Pay a Bill
  • Patient & Visitor Resources
  • Disabilities Resource Center
  • Services
  • Medical Records
  • No Surprises Act
  • Price Transparency
  • Financial Assistance
  • Classes & Events
  • Health Library
Health Care Professionals
  • Physician Information
  • Resources
  • Education & Training
  • Departments
  • Credentialing
Newsroom
  • Newsroom Home
  • Inside Life Changing Medicine Blog
  • News Releases
About
  • Why UPMC
  • Facts & Stats
  • Supply Chain Management
  • Community Commitment
  • Financials
  • Supporting UPMC
  • HealthBeat Blog
  • UPMC Apps
  • UPMC Enterprises
  • UPMC Health Plan
  • UPMC International
  • Nondiscrimination Policy
Life changing is...
Follow UPMC
  • Contact Us
  • Website/Email Terms of Use
  • Medical Advice Disclaimer
  • Privacy Information
  • Active Privacy Alerts
  • Sitemap
© 2025 UPMC I Affiliated with the University of Pittsburgh Schools of the Health Sciences Supplemental content provided by Healthwise, Incorporated. To learn more, visit healthwise.org
Find Care
Providers
Video Visit
Portal Login