Hepatitis A

Diagnosing Hepatitis A

Three out of every four adults who get hepatitis A have symptoms that usually develop over a period of several days.

Hepatitis A does not always cause symptoms, but adults are more likely to have symptoms than children.

Symptoms of hepatitis A

• Tiredness
• Loss of appetite
• Fever
• Nausea
• Abdominal pain or discomfort
• Jaundice (yellowing of the eyes and skin)
• Darker colored urine
• Rash

A person can spread the hepatitis A virus (HAV) about one week before symptoms appear and during the first week of symptoms.

People with no symptoms can still spread the virus. This often happens with young children who unknowingly spread HAV to older children and adults.

Unlike hepatitis B and hepatitis C, hepatitis A causes no long-term liver damage and usually does not cause death.

There is no chronic carrier state with hepatitis A. Having had the disease produces lifelong immunity from future hepatitis A virus infection.

Testing for hepatitis A

To diagnose hepatitis A, your doctor will ask about your symptoms and medical history, and perform a physical exam.

Tests may include:

• Blood tests — to look for hepatitis A antibodies (proteins that your body has made to fight the hepatitis A virus)
• Liver function studies
• Liver biopsy — removal of a sample of liver tissue to be examined (only in severe cases) 

Hepatitis A Treatment

There are no specific treatments for hepatitis A.

The goals of hepatitis A treatment are to:

• Keep you as comfortable as possible
• Prevent the infection from being passed to others
• Prevent more liver damage by helping you avoid substances (medications, alcohol) that might stress the liver while it's healing

The disease generally will go away, without treatment, within two to five weeks. However, about 15 percent of people who are infected by hepatitis A will have relapsing symptoms for up to nine months.

In almost all cases, once you recover, there are no aftereffects and you are immune to the virus.

In rare cases, hepatitis A infection will be so severe that a liver transplant may be necessary.

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Learn more about treatments at the UPMC Liver Cancer Center.

Hepatitis A Prevention

The hepatitis A virus (HAV) is usually found in stool (bowel movement).

Here are a few you ways you can protect yourself from infection.

Proper sanitary habits

• Wash your hands with soap and water before eating or preparing food.
• Wash your hands with soap and water after using the bathroom or changing a diaper.
• Carefully clean all household utensils after use by a person infected with HAV.
• Avoid using household utensils that a person infected with hepatitis A may have touched.
• Avoid sexual contact with a person infected with hepatitis A.
• Avoid injected drug use, especially with shared needles.

Immune (gamma) globulin

Immune (gamma) globulin is a preparation containing antibodies that provides temporary protection from hepatitis A (about one to three months).

You must receive it before exposure to the virus, or within two weeks after exposure to HAV.

Hepatitis A vaccine

This vaccine is made from inactive hepatitis A virus, and is highly effective in preventing infection.

It provides protection from infection for:

• Four weeks, following the first injection
• Up to 20 years, following a second injection

Licensed for those over two years of age, the vaccine is recommended for:

• People who have chronic liver diseases or clotting factor disorders
• Those who have close physical contact with people who live in areas with poor sanitary conditions
• People traveling to countries where sanitary conditions are poor
• Children who live in areas that have repeated hepatitis A epidemics
• People who inject illicit drugs
• Men who have sex with men

Notes about the hepatitis A vaccine

• It's unclear how safe the vaccine is for women who are pregnant.
• The vaccine should not be given to children under two years old.
• Check with your doctor to see if you should receive the vaccine, and if so, how many injections you should have.

Can the hepatitis A virus be killed?

The virus is killed by heating to 185 F (85 C) for one minute. However, the disease can still be spread by cooked foods if they are contaminated after cooking.

Adequate chlorination of water, as recommended in the United States, kills HAV.