Coronary artery disease is the most common type of heart disease and the leading cause of death in the United States for both men and women.
The UPMC Heart and Vascular Institute's team of specialists offers medical and surgical options to manage and treat coronary artery disease.
Most people with CAS are between the ages of 40 and 70. The prevalence of CAS decreases after age 70.
CAS is rare and accounts for only two out of every 100 cases of angina.
Kounis syndrome is a little-known form of CAS caused by an allergic reaction to mediators of inflammation, such as histamines and leukotrienes.
Kounis syndrome is also known as allergic angina or allergic myocardial infarction.
CAS happens when your heart's blood vessels narrow. This lessens the supply of oxygen to your heart muscle, causing painful spasms.
Triggers for these spasms include:
In some cases, CAS can form without a known cause or trigger.
CAS is more common in men than women.
Left undiagnosed or untreated, it can lead to serious complications, including:
When there's no heart blockage, CAS is the main cause of ischemic, or coronary heart disease. That's when the heart isn't getting enough oxygen or blood.
About 50% of people with angina (chest pain and pressure), and 57% of people with acute coronary syndrome have CAS.
Medical care and lifestyle changes are the mainstays of treating and preventing CAS.
To help prevent CAS:
Women's hearts differ from those of men. Heart disease can cause different symptoms in both women and men.
At Magee-Womens Heart Program, we know those differences and take them seriously. We're here to help all our patients — women and men — overcome heart problems.
These sensations often occur on the left side of your chest or under your sternum or chest bone. The pain may also move to your neck, jaw, and left arm.
CAS mostly occurs when you're resting. The spasms can be painful enough to wake you up. They can also occur during normal daily activity.
CAS episodes usually last 15 minutes. In some cases, spasms are silent and you won't feel any symptoms.
Often a chronic condition, CAS episodes can happen many times a day, yearly (or less), or something in between.
If you have CAS, call 911 or go to the emergency room if:
CAS can be hard to diagnose. If your doctor suspects you have CAS they should do a complete cardiovascular exam.
They may also want to do one or some of the following tests:
When treating CAS, the goals are to:
Along with suggesting lifestyle changes, doctors mainly treat CAS with medicine.
Your doctor may instruct you to place one or more nitroglycerin tablets under your tongue during a CAS attack. This helps relax your heart arteries to reduce chest pain and control spasms.
If your symptoms don't improve after taking it, seek medical help right away. Only a health care professional can tell whether you're having a heart attack.
Common drugs to help prevent CAS attacks include:
After six to 12 months of treatment, your doctor may reduce your medication. Or you may need to stay on it long-term.
CAS is often a chronic condition. Between 4% to 19% of people have repeat episodes.
The prognosis for CAS depends on your age.
Some people may get acute coronary syndrome, an umbrella term for the sudden blockage of blood flow to the heart muscle. These people have a higher risk of poor prognosis if they're older or have an impaired left heart ventricle.
The risk for an event such as a heart attack is highest three months after a CAS attack.
For most, the outlook for CAS is good as long as you take your medicine and reduce risk factors, such as smoking.
The UPMC Heart and Vascular Institute offers educational information and videos about coronary artery disease and other heart and vascular conditions.
Many people find these resources helpful in answering their questions about their heart disease and preparing them for their procedure or diagnostic test.
The links below will open a new browser window.
For an appointment at the UPMC Heart and Vascular Institute, complete an appointment request form or call 1-855-876-2484 (UPMC-HVI).