Skip to Content
800-533-8762
  • Careers
  • Newsroom
  • Health Care Professionals
  • About Us
  • Contact Us
UPMC
  • Find a Doctor
  • Services
    • Frequently Searched Services
    • Frequently Searched Services
      Allergy & Immunology Behavioral & Mental Health Cancer Ear, Nose & Throat Endocrinology Gastroenterology Heart & Vascular Imaging Neurosciences Orthopaedics
      Physical Rehabilitation Plastic & Reconstructive Surgery Primary Care Senior Services Sports Medicine Telemedicine Transplant Surgery Walk-In Care Weight Management Women’s Health
      See all Services
    • Services by Region
    • Find a UPMC health care facility close to you quickly by browsing by region.
      UPMC in Western Pa. Western Pa. and New York
      UPMC in Central Pa. Central Pa.
      UPMC in North Central Pa. North Central Pa.
      UPMC in Western Md. Maryland & West Virginia
    • See All Services
  • Locations
    • Locations by Type
    • Locations by Type
      UPMC hospitals
      Hospitals
      Physical Therapy
      Physical Therapy
      Urgent care
      Walk-In Care
      UPMC Outpatient Centers
      Outpatient Centers
      UPMC Imaging Services
      Imaging
      Community Health Centers
      Community Health Centers
      See All Locations
    • Locations by Region
    • Locations by Region
      UPMC in Southwest Pa. Southwest Pa.
      UPMC in North Central Pa. North Central Pa.
      UPMC in Northwest Pa and Ny. Northwest Pa. & Western N.Y.
      UPMC in West Central Pa. West Central Pa.
      UPMC in Central Pa. Central Pa.
      UPMC in Western Md. Maryland & West Virginia
    • See All Locations
  • Patients & Visitors
    • Patient & Visitor Resources
    • Patient & Visitor Resources
      Patients and Visitors Resources Pay a Bill Classes & Events Medical Records Health Library Patient Information
      Patient Portals Privacy Information Shared Decision Making Traveling Patients Visitor Information
      Man uses mobile phone
      Pay a Bill
      Nurse reviews medical chart
      Request Medical Records
  • Patient Portals
  • Find Covid-19 updates
  • Schedule an appointment
  • Request medical records
  • Pay a bill
  • Learn about financial assistance
  • Find classes & events
  • Send a patient an eCard
  • Make a donation
  • Volunteer
  • Read HealthBeat blog
  • Explore UPMC Careers
Skip to Content
UPMC
  • Patient Portals
  • For Patients & Visitors
    • Find a Doctor
    • Locations
    • Patient & Visitor Resources
    • Pay a Bill
    • Services
    • More
      • Medical Records
      • Financial Assistance
      • Classes & Events
      • HealthBeat Blog
      • Health Library
  • About UPMC
    • Why UPMC
    • Facts & Stats
    • Supply Chain Management
    • Community Commitment
    • More
      • Financials
      • Support UPMC
      • UPMC Apps
      • UPMC Enterprises
      • UPMC International
  • For Health Care Professionals
    • Physician Information
    • Resources
    • Education & Training
    • Departments
    • Credentialing
  • Careers
  • Contact Us
  • Newsroom
  • UPMC >
  • Our Services >
  • Heart & Vascular >
  • Conditions We Treat >
  • Hyperlipidemia
Heart & Vascular
About Us
Conditions We Treat
Abdominal Aortic Aneurysm
Adult Congenital Heart Disease
Adventitial Cystic Disease
Aneurysms
Angina
Aortic Coarctation
Aortic Disease
Aortic Dissection
Aortic Root Aneurysm
Aortic Stenosis
Aortoiliac Occlusive Disease
Aortopathy
Arrhythmia
Arrhythmogenic Right Ventricular Cardiomyopathy
Arteriovenous Malformation
Ascending Aortic Arch Aneurysm
Atherosclerosis
Atrial Fibrillation
AV Fistula
Bicuspid Aortic Valve
Brachiocephalic Arterial Insufficiency
Bradycardia
Brugada Syndrome
Buergers Disease
Cardiac Amyloidosis
Cardiac Arrest
Cardiomyopathy
Carotid Artery Disease
Carotid Artery Stenosis
Chronic Coronary Total Occlusion
Chronic Mesenteric Ischemia
Chronic Venous Insufficiency
Connective Tissue Disorder
Coronary Artery Disease
Coronary Vasospasm
Deep Vein Thrombosis
Diabetic Arterial Disease
Dilated Cardiomyopathy
Dysphagia Lusoria
Familial Lipid Syndrome
Fibromuscular Dysplasia
Foot Leg Ulcers
Gestational Hypertension
Giant Cell Arteritis
Heart Disease
Heart Failure
Heart Murmurs
Heart Palpitations
Heart Valve Disease
Hypercholesterolemia
Hyperlipidemia
Hypertrophic Cardiomyopathy
Infective Endocarditis
Left Ventricular Cardiomyopathy
Long QT Syndrome
Lyme Carditis
Lymphedema
Marfan Syndrome
May Thurner Syndrome
Mitral Valve Disease
Mitral Valve Regurgitation
Mitral Valve Stenosis
Myocarditis
Nutcracker Syndrome
Pediatric Congenital Heart Disease
Pericarditis
Peripartum Cardiomyopathy
Peripheral Aneurysm
Peripheral Artery Disease
Peripheral Venous Disease
Popliteal Artery Entrapment Syndrome
Postpartum Hypertension
Postural Orthostatic Tachycardia Syndrome
Premature Ventricular Contraction
Pulmonary Embolism
Spontaneous Coronary Artery Dissection
Tachycardia
Thoracic Aortic Aneurysm
Thoracic Outlet Syndrome
Varicose Spider Veins
Vascular Malformations
Vascular Trauma
Vasculitis
Vasospastic Disorder
Venous Thromboembolism
Venous Ulcer
Visceral Artery Aneurysm
Wolff Parkinson White Syndrome
Our Services
For Patients
For Professionals & Students
Our Locations
Contact Us
Heart & Vascular
About Us
Conditions We Treat
Abdominal Aortic Aneurysm
Adult Congenital Heart Disease
Adventitial Cystic Disease
Aneurysms
Angina
Aortic Coarctation
Aortic Disease
Aortic Dissection
Aortic Root Aneurysm
Aortic Stenosis
Aortoiliac Occlusive Disease
Aortopathy
Arrhythmia
Arrhythmogenic Right Ventricular Cardiomyopathy
Arteriovenous Malformation
Ascending Aortic Arch Aneurysm
Atherosclerosis
Atrial Fibrillation
AV Fistula
Bicuspid Aortic Valve
Brachiocephalic Arterial Insufficiency
Bradycardia
Brugada Syndrome
Buergers Disease
Cardiac Amyloidosis
Cardiac Arrest
Cardiomyopathy
Carotid Artery Disease
Carotid Artery Stenosis
Chronic Coronary Total Occlusion
Chronic Mesenteric Ischemia
Chronic Venous Insufficiency
Connective Tissue Disorder
Coronary Artery Disease
Coronary Vasospasm
Deep Vein Thrombosis
Diabetic Arterial Disease
Dilated Cardiomyopathy
Dysphagia Lusoria
Familial Lipid Syndrome
Fibromuscular Dysplasia
Foot Leg Ulcers
Gestational Hypertension
Giant Cell Arteritis
Heart Disease
Heart Failure
Heart Murmurs
Heart Palpitations
Heart Valve Disease
Hypercholesterolemia
Hyperlipidemia
Hypertrophic Cardiomyopathy
Infective Endocarditis
Left Ventricular Cardiomyopathy
Long QT Syndrome
Lyme Carditis
Lymphedema
Marfan Syndrome
May Thurner Syndrome
Mitral Valve Disease
Mitral Valve Regurgitation
Mitral Valve Stenosis
Myocarditis
Nutcracker Syndrome
Pediatric Congenital Heart Disease
Pericarditis
Peripartum Cardiomyopathy
Peripheral Aneurysm
Peripheral Artery Disease
Peripheral Venous Disease
Popliteal Artery Entrapment Syndrome
Postpartum Hypertension
Postural Orthostatic Tachycardia Syndrome
Premature Ventricular Contraction
Pulmonary Embolism
Spontaneous Coronary Artery Dissection
Tachycardia
Thoracic Aortic Aneurysm
Thoracic Outlet Syndrome
Varicose Spider Veins
Vascular Malformations
Vascular Trauma
Vasculitis
Vasospastic Disorder
Venous Thromboembolism
Venous Ulcer
Visceral Artery Aneurysm
Wolff Parkinson White Syndrome
Our Services
For Patients
For Professionals & Students
Our Locations
Contact Us

Chat Keywords List

  • cancel or exit: Stops your conversation
  • start over: Restarts your current scenario
  • help: Shows what this bot can do
  • terms: Shows terms of use and privacy statement
  • feedback: Give us feedback
Continue
Chat with UPMC
RESTART
MENU
CLOSE

Familial Hyperlipidemia

Hyperlipidemia defines an elevated level of lipids — like cholesterol and triglycerides — in your blood. Doctors link this disease to atherosclerosis (hardening of the arteries) and other serious conditions like heart attack, stroke, and peripheral artery disease.

Looking For Hyperlipidemia Care?

Related services:

  • Heart and Vascular

Find a Provider

On this page

  • What Is Hyperlipidemia?
  • What Are The Symptoms Of Hyperlipidemia?
  • How Do You Diagnose Hyperlipidemia?
  • How Do You Treat Hyperlipidemia?

What Is Hyperlipidemia?

Lipids — like cholesterol and triglycerides — are a type of fat in the blood. You need lipids to function, but too much of this fat puts you at risk for certain health problems.

People with too much cholesterol and triglycerides have hyperlipidemia, which can increase their risk of:

  • Heart disease
  • Stroke
  • Artery disease

What are the types of hyperlipidemia?

  • Acquired hyperlipidemia — may be from certain behaviors you do (or don't do). Other times, medicine or other health problems can cause the disease. Some people acquire it from their parents.
  • Familial hypercholesterolemia — is one type of genetic hyperlipidemia. A change in the gene that moves cholesterol out of the body instead causes it to build up on the artery walls.
  • Familial hypertriglyceridemia — is another type of genetic hyperlipidemia. It causes triglyceride levels to become too high.

What causes hyperlipidemia?

Acquired hyperlipidemia — has a few possible causes:

  • Eating a high-fat diet.
  • Being inactive or not getting enough exercise.
  • Being obese.
  • Having another disease, like diabetes.
  • Menopause in women.

Familial hyperlipidemias — occur when a parent passes on the genes that cause these conditions.

What are hyperlipidemia risk factors and complications?

Anyone can be at risk for acquired hyperlipidemia, but it often occurs in people who:

  • Are overweight and idle.
  • Have other health issues.
  • Take certain drugs.

You're at risk for genetic hyperlipidemia if a family member has it. If so, you should have a test for the disease.

Hyperlipidemia can cause fatty deposits, known as plaque, to build up on the body's blood vessel walls.

Plaque can cause problems such as:

  • Atherosclerosis, or hardened arteries.
  • Coronary heart disease when blood vessels can't provide enough oxygen to the heart.
  • Heart attack.
  • Stroke.
  • Peripheral artery disease, or disease in the vessels of the arms or legs.

Back to top


What Are The Signs And Symptoms Of Hyperlipidemia?

If you have hyperlipidemia, you might not have any symptoms.

But, as it gets worse, you might notice:

  • Leg cramps, mostly in your calves.
  • Pain in your feet or toes.
  • Chest pain.
  • Trouble breathing, or shortness of breath when you're active.
  • Confusion or trouble speaking.
  • Weakness, often in your arm.

Back to top


How Do You Diagnose Hyperlipidemia?

Providers at UPMC use blood tests to diagnose hyperlipidemia.

They'll also ask you about your family history and any other health problems you have.

Back to top


How Do You Treat Hyperlipidemia?

Doctors might suggest lifestyle changes, such as being more active and eating healthier foods.

They might also prescribe medication to lower lipid levels.

At your first visit, you'll meet with our:

  • Food and nutrition expert to discuss your current diet and changes you should make.
  • Pharmacist to look at your current meds and any new drugs that might be right for you.
  • Heart doctor to learn about your health and family history, and to go over any test results.

Your care team will then design a hyperlipidemia treatment plan that supports your health goals. It might also include follow-up visits with other UPMC experts.


By UPMC Editorial Staff. Last reviewed on 2024-10-01.

UPMC
200 Lothrop Street Pittsburgh, PA 15213

412-647-8762 800-533-8762

Patients And Visitors
  • Find a Doctor
  • Locations
  • Pay a Bill
  • Patient & Visitor Resources
  • Disabilities Resource Center
  • Services
  • Medical Records
  • No Surprises Act
  • Price Transparency
  • Financial Assistance
  • Classes & Events
  • Health Library
Health Care Professionals
  • Physician Information
  • Resources
  • Education & Training
  • Departments
  • Credentialing
Newsroom
  • Newsroom Home
  • Inside Life Changing Medicine Blog
  • News Releases
About
  • Why UPMC
  • Facts & Stats
  • Supply Chain Management
  • Community Commitment
  • Financials
  • Supporting UPMC
  • HealthBeat Blog
  • UPMC Apps
  • UPMC Enterprises
  • UPMC Health Plan
  • UPMC International
  • Nondiscrimination Policy
Life changing is...
Follow UPMC
  • Contact Us
  • Website/Email Terms of Use
  • Medical Advice Disclaimer
  • Privacy Information
  • Active Privacy Alerts
  • Sitemap
© 2025 UPMC I Affiliated with the University of Pittsburgh Schools of the Health Sciences Supplemental content provided by Healthwise, Incorporated. To learn more, visit healthwise.org
Find Care
Providers
Video Visit
Portal Login