Learn more about the UPMC Center for Inherited Heart Disease experts.
In LVNC, muscle in the heart's left ventricle — one of two lower chambers — becomes thick, with space between muscle fibers. These changes make the muscle weak and affect how the left chamber pumps blood.
Doctors estimate LVNC affects around 10 out of a million people each year.
But they don't know this with certainty since some people with LVNC don't have any symptoms.
Doctors don't always know what causes LVNC.
Sometimes, parents pass it on to their kids through genes. These mutated genes can cause changes in how a baby's heart forms while in the womb. This can lead to LVNC.
Other times, the gene mutations happen without any family history of the disease. You might be the first in your family to have LVNC.
Some people with LVNC have other heart conditions like dilated cardiomyopathy.
You might be at risk for LVNC if you have:
LVNC can cause complications, including:
Our center has experts who diagnose and treat genetic heart diseases, including LVNC.
Our team offers:
If you have LVNC, you might not have any symptoms at all or even know you have the disease.
Talk to your doctor if you have symptoms such as:
Let your doctor know if you have family members who've had sudden cardiac arrest, heart failure, or a heart attack.
At the UPMC Center for Inherited Heart Disease, you'll see a heart doctor and genetic counselor. They'll screen you for LVNC and ask about your family history of heart disease.
Tests for LVNC include:
Your care team at the UPMC Center for Inherited Heart Disease will create a tailored plan to treat your LVNC. Your treatment will depend on your symptoms.
Treatment goals include managing any symptoms and reducing your risk of complications.
Your doctor might prescribe certain drugs to treat LVNC.
If needed, your doctor might talk to you about:
Your physician may also discuss tailored lifestyle changes to help you better manage your LVNC.