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Regenerative Medicine for Orthopaedic Injuries

Orthopaedic injuries can compromise mobility and hinder quality of life, and not just for professional athletes. At the McGowan Institute for Regenerative Medicine, we've been studying the forces on bones and joints for a long time. We’ve been working on:

  • Better ways to help heal orthopaedic injuries
  • Better artificial joints
  • Replacement tissue for cartilage and ligaments

Much of what we've learned has already improved surgical and rehabilitation techniques for orthopaedic injuries.

One of the first regenerative medicine treatments to become a commercial product, a scaffold called SIS (Small Intestinal Submucosa) that promotes the regrowth of soft tissue, is used to help regenerate shoulder rotator cuffs and knee ligaments. McGowan Institute deputy director Stephen Badylak, MD, pioneered this biologic material that has been effective in certain cases. Read more.

In the laboratory of McGowan Institute affiliated faculty member Prashant Kumta, PhD, one of the lab’s visions is to revolutionize metallic biomaterials and technologies to create life changing devices. This will lead to engineered systems that will interface with the human body to prolong and improve quality of life, specifically with craniofacial and orthopaedic applications. Dr. Kumta and his team’s goal is to engineer logical and clinically relevant options that could regenerate mineralized tissue (bone/tooth) formation utilizing a unique combination of evolutionary load-bearing biodegradable materials (metals), growth factors, and cell therapy. Read more.

Contact Us

McGowan Institute for Regenerative Medicine
Bridgeside Point II 
450 Technology Drive
Suite 300
Pittsburgh, PA 15219

Read information on campus shuttles.

Phone: 412-624-5500
Fax: 412-624-5363

Additional Resources

Additional Resources

The work described here—unless noted otherwise—are research projects in various stages of maturity.

For clinically available therapies, please follow the link below.

How Do I Get Treatment?

Expert orthopaedic surgical care is available at Orthopaedic Surgery Services at UPMC.