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The lack of available functional substitutes for native skeletal muscle tissue hampers the reconstruction of lost tissue due to:
Initial studies have focused on the use of small intestinal submucosa (SIS) scaffolds to replace partial lost calf muscle and Achilles tendon.
These studies have shown that SIS is able to stimulate restoration of:
This new muscle growth includes a mixed muscle fiber type much like the lost native muscle. It's able to both contract and react to nerve impulses.
McGowan Institute researchers in muscle tissue regrowth include: