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Brooke S. G. Molina, PhD, is professor of Psychiatry, Psychology, and Pediatrics at University of Pittsburgh and UPMC Western Psychiatric Hospital. She directs clinical research at the ADHD Across the Lifespan Program. This long-time longitudinal clinical research involves youth/adolescents and adult patients. This episode presents information on life-time course prediction, drug misuse, and primary care-based strategies for management of ADHD.