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Psychiatry Advances Podcast Series

Discover innovative research and patient-centered programs at the cutting edge of psychiatry and behavioral health sciences on the Psychiatry Advances podcast series.

Psychiatric, psychological, nursing, and rehabilitative professionals will enjoy this podcast from UPMC Western Psychiatric Hospital, a national leader in the innovative treatment of mental health and addictive disorders.

Meet the Host

Loren Roth, MD, MPH, is a distinguished professor emeritus of Psychiatry. He continues to actively teach and work at UPMC Western Psychiatric Hospital. He is also the former chief medical officer of UPMC, as well as the previous associate senior vice chancellor for Clinical Policy and Planning, Health Sciences, at the University of Pittsburgh.

Listen to Our Latest Episode

Brain Science, Clozapine and Early Intervention in Psychosis

Dr. Deepak Sarpal is Assistant Professor of Psychiatry/Medical Director of Services for Treatment of Early Psychosis at WPH. This Podcast focuses upon Clozapine, a very valuable but underused treatment for refractory schizophrenia, also brain science involving functional imaging associated with patient improvement on anti-psychotic drugs. Findings include brain pre-frontal cortex connectivity and synchronization of function with brain striatum, limbic system structures, Globus Pallidus.


Tarcijonas, G, Sarpal, DK, Neuroimaging markers of antipsychotic treatment response in Schizophrenia: An overview of magnetic resonance imaging studies. Neurobiology of Disease 131 (2019)

Tarcijonas, G, Foran, W, Haas, GL, Luna, B, Sarpal, DK. Intrinsic Connectivity of the Globus Pallidus: An Uncharted Marker of Functional Prognosis in People with First-Episode Schizophrenia, Schizophrenia Bulletin 46 (2020) pgs. 184-192

Released: 2/10/21

Archived Episodes 

Contact Us

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This podcast is for informational and educational purposes only and is not to be considered medical or behavioral health advice for any particular patient. Clinicians must rely on their own informed clinical judgments when making recommendations for their patients. Patients in need of medical or behavioral health advice should consult their personal health care provider.