Jordan Karp, MD, is professor of psychiatry, anesthesiology, and clinical and translational science at the University of Pittsburgh and UPMC Western Psychiatric Hospital. He is an internationally recognized expert in the field of geriatric psychiatry. Late-life depression may be brain “toxic.” This episode discusses geriatric depression and ongoing multisite PCORI/NIH geriatric research about a treatment-resistant depression (OPTIMUM/OPTIMUM-Neuro) trial. This comparative effectiveness research includes patient – cognition results and brain imaging.
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