Skip to Content


UPMC Content 3

Restylane is made from hyaluronic acid, a natural substance found in the human body that plumps up the skin. Because Restylane is a natural filler, no allergic testing is needed prior to treatment. This FDA-approved therapy has been used since 1996.

Small amounts of Restylane are injected with a fine needle under moderate to severe wrinkles and lines in the face such as:

  • Crow’s feet
  • Forehead creases and "laugh lines" (nasolabial folds)

The procedure generally takes 15 to 20 minutes, and you can immediately resume normal activity. A local anesthetic may be used to minimize discomfort.

Results typically last for six months. Your results may last up to 18 months with a follow-up treatment. Side effects may include redness or swelling that lasts less than seven days.

Restylane® is a registered trademark of HA North American Sales AB.

Contact the UPMC Cosmetic Surgery and Skin Health Center

Complete our Contact Us form or contact one of our offices directly.


2100 Georgetown Drive
Suite 400
Sewickley, PA 15143


5401 Walnut Street
Suite 300
Pittsburgh, PA 15232