UPMC Hillman Cancer Center at UPMC Horizon provides patients access to the latest cancer therapies and groundbreaking research right in their neighborhoods. Our three locations — Shenango Valley, Greenville, and New Castle — all feature bright, modern, spacious treatment areas designed with patient comfort in mind.
UPMC Hillman Cancer Center at UPMC Horizon is accredited by the American College of Surgeons Commission on Cancer and the American College of Radiation Oncology. UPMC Hillman Cancer Center is the region’s only National Cancer Institute-designated Comprehensive Cancer Center.
The UPMC Hillman Cancer Center medical oncology locations in Farrell, Greenville, and New Castle provide medical oncology treatment for many types of cancer as well as access to most of the clinical trials available in Pittsburgh.
Radiation oncology uses a linear accelerator to deliver radiation directly to a cancerous tumor. The technology available at UPMC Hillman Cancer Center at UPMC Horizon for radiation therapy is the latest in state-of-the-art cancer treatment. Methods and equipment including respiratory gating, which tracks a tumor’s position during treatment as the patient breathes or makes other movements, and RapidArc®, which rotates 360 degrees around a patient’s body to deliver targeted treatments of higher doses of radiation, helps ensure accuracy and precision of radiation therapy. Radiation oncology treatment is available at our Shenango Valley location.
Through UPMC Horizon and UPMC Jameson, state-of-the-art diagnostic services are available for cancer patients either on-site at the UPMC Hillman Cancer Center locations or nearby in the community.
Learn more about imaging services at UPMC Horizon and UPMC Jameson
In March 2025, UPMC Hillman Cancer Center at UPMC Horizon–Shenango Valley unveiled its second linear accelerator, ensuring expanded access to world-class cancer care for patients in Mercer and Lawrence counties. The state-of-the art machine delivers high-energy, external beam radiation treatments that precisely target a variety of cancer tumors in the body. Hear more from UPMC Hillman radiation oncologist Uzoma Iheagwara, MD, PhD, in the following video.
Specialists with the Magee-Womens Gynecologic Cancer Program see patients locally at the UPMC Specialty Care in Hermitage, offering evaluation and treatment for ovarian, cervical, uterine, vulvar, and vaginal cancer.
Learn more about the Magee-Womens Gynecologic Cancer ProgramProviders from UPMC Magee-Womens Surgical Associates see breast surgery patients at offices in Hermitage and New Castle. UPMC Horizon and UPMC Jameson also offer convenient access to diagnostic imaging services including digital mammography, 3D mammography, stereotactic breast biopsy, breast ultrasound, and ultrasound-guided breast biopsy. Breast health providers work closely with medical and radiation oncologists to develop treatment plans for breast cancer patients.
Take a virtual tour of UPMC Hillman Cancer Center facilities in Lawrence and Mercer counties.
UPMC Hillman Cancer Center at UPMC Horizon
2200 Memorial Drive
Farrell, PA 16121
Medical Oncology: 724-983-7021
Radiation Oncology: 724-983-7570
110 N. Main St.
Greenville, PA 16125
Medical Oncology: 724-589-4318
3410 Wilmington Road
New Castle, PA 16105
Medical Oncology: 724-658-7300
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