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The McGowan Institute for Regenerative Medicine is working on several devices that oxygenate blood before it arrives in the lungs. While mechanical ventilators can assist patients with breathing for short periods of time, they sometimes cause lung damage. In addition, they're not particularly portable.
Under the direction of McGowan Institute for Regenerative Medicine faculty member William Federspiel, PhD, the Medical Devices Laboratory is developing clinically significant devices for the treatment of pulmonary and cardiovascular ailments by utilizing engineering principles of fluid flow and mass transfer. Advancement of novel respiratory support devices is being conducted for the treatment of acute and acute-on-chronic lung failure. Also, medical devices utilizing membrane and particle based adsorption technologies for the removal of targeted solutes from whole blood is an ongoing effort which will aid in the treatment of pathogenic reactions.
Examples of on-going respiratory assistance research projects within the Medical Devices Laboratory include:
While there are only about 200 pediatric patients in the U.S. each year who need such devices, there are between 10,000 and 50,000 adult patients who need the higher-flow assistance. There are an additional 100,000 to 300,000 patients in the U.S. who need the CO2 removal devices.
Learn more about the wearable artificial lung.
As these technologies mature, they will be available to physicians to assist in advanced lung care cases.