What Is Living-Donor Kidney Transplant Surgery?
There are two options for kidney transplants: living donors and deceased donors. With some kidney transplants, surgeons remove the organ from a deceased donor. At UPMC, we believe in the power of living donation and consider it a first-line treatment option.
During a living-donor kidney transplant, a surgeon will remove a healthy kidney from a living donor — whether a relative, friend, or stranger — and transplant it into the person with kidney failure. Kidney donation is a personal decision and should be considered only after being fully informed of the process.
Advantages of receiving a living-donor kidney
- There is no need to wait for a deceased donor kidney to become available. Most living transplants take place within months of an evaluation.
- The kidney usually begins to work immediately, even in the operating room.
- There are fewer episodes of rejection. As a result, living donor kidneys tend to last longer than deceased donor kidneys.
- Depending on the genetic match, the recipient may be able to take fewer immunosuppressive drugs, therefore minimizing possible side effects.
- Living-donor kidney transplants can be scheduled at a convenient time for both the donor and recipient. This allows both the donor and the recipient to plan for absences from work and family responsibilities.
What are the types of living kidney donation?
There are three types of living kidney donation:
- Directed kidney donation — A living donor chooses a recipient for their kidney. Often, donations are made by family members or close friends.
- Nondirected kidney donation — Also known as an altruistic donation, a living donor gives their kidney to someone they don’t know. The donation may be anonymous.
- Paired kidney donation — Also known as a “swap,” this occurs when two or more kidney recipients trade willing donors. Paired donations occur when a living kidney donor and their intended recipient are not a match.
Where does UPMC offer living-donor kidney transplant?
UPMC performs living-donor kidney transplants at UPMC Montefiore in Pittsburgh, Pa., UPMC Hamot in Erie, Pa., and UPMC Harrisburg in Harrisburg, Pa. Each location combines specialized kidney care with comprehensive resources to deliver life-changing treatment options for patients.
What Conditions Do We Treat?
We provide comprehensive transplant care — from your pretransplant exam to living donor and transplant surgery — for recipients with end-stage kidney disease and their living kidney donors.
Who’s Eligible for Living-Donor Kidney Transplant?
Living donors can be family members, friends, or even strangers who are willing to help. A patient on the national kidney transplant waiting list and their potential living donor don’t even need to have the same blood type.
To be a living donor, you need to be physically and mentally healthy, with no history of illnesses involving any major organs, as this could complicate surgery.
Who is eligible to be a living kidney donor?
To become a living donor, you must:
- Be between the ages of 18 and 75.
- Be in good health. Conditions such as uncontrolled high blood pressure, cancer, HIV, hepatitis, or other disorders could prevent kidney donation.
- Meet all other living kidney donor eligibility requirements.
The transplant team at UPMC assesses potential kidney donors to ensure you are a suitable match for organ donation. We request that donors have a selfless motivation when considering helping someone in need of a life-saving kidney transplant.
Do I need to be a relative of the person who receives my kidney?
Although many people wish to donate their kidney to a family member, you can also donate to an unrelated person.
In some kidney transplant cases — depending on a blood type match and other requirements — donors can take part in a kidney exchange or “swap,” also known as a paired donation. This means two or more pairs of related donors and recipients donate to each other.
What are the risks of living-donor kidney surgery?
Research has shown that there is little long-term risk or effect on a living kidney donor.
But, as with any major surgery, kidney donation surgery can include complications such as:
- Bleeding.
- Infection.
- Blood clots.
Death is very rare but has occurred in a few cases.
Who is eligible to receive a living donor kidney?
Anyone who needs a kidney transplant is eligible to receive a kidney from a living donor. However, the donated kidney must be a suitable match for the recipient to reduce the risk of complications after transplantation.
What Living-Donor Kidney Transplant Services Do We Offer?
Living-donor kidney transplant services include:
Living-donor kidney transplant
During a living-donor kidney transplant, a surgeon removes one kidney from a healthy adult and transplants it into a patient with end-stage kidney disease. This procedure is possible because, although you have two kidneys, you can live a perfectly healthy life with only one working kidney.
Minimally invasive robotic surgery for living kidney donors
- UPMC surgeons use advanced technologies and robotic systems to assist with transplant surgery. As a result, we use exclusively minimally invasive robotic techniques to perform living donor kidney surgeries. Using a robotic system instead of traditional surgical techniques or open surgery allows surgeons to perform minimally invasive living donor surgical procedures with increased precision, less tissue damage, and better visualization — providing easier access to areas that are hard to reach.
- In 2024, UPMC kidney transplant surgeons performed a robotic nephrectomy on a living donor using the multiport robotic surgery system, da Vinci Xi® by Intuitive. The UPMC Kidney Transplant Program at UPMC Harrisburg was the first program in central Pennsylvania to use this robotic system.
Supportive services for living-donor kidney transplant
Living donor mentors
UPMC offers the opportunity for potential living kidney donors to speak with someone who has already been a living donor. If you’d like to connect with a mentor who can share their personal experience with you, please reach out to your transplant coordinator or living donor liaison.
Training on finding a living kidney donor
Our Living Donation Liaison offers online training sessions each month to educate those who need kidney transplants — and their support people — on the process of finding a living donor. Participants learn about the benefits of living donation, common concerns, best practices, and ideas to start or expand their search.
By the end of the training sessions, participants will have a written plan for taking action. For additional information, please contact your transplant coordinator or living donor liaison.
What Can I Expect?
Living-donor kidney transplants help save the lives of people with end-stage kidney disease by reducing their time or eliminating the need to be placed on the national transplant waiting list. Living-donor kidney recipients often have improved outcomes and a quicker recovery.
Living donors are given the rare chance to save someone else’s life and see their friend or loved one return to health and happiness.
During the process, living kidney donors can expect:
Pre-kidney-donation evaluation
Before scheduling living-donor kidney surgery, you will undergo a thorough pre-kidney-donation evaluation.
The living kidney donor evaluation involves several steps. Potential donors will meet with all members of the living donor team during this process.
The team includes:
- Dietitians.
- Independent living donor advocate.
- Nurse coordinators.
- Pharmacists.
- Physicians.
- Social workers.
- Surgeons.
All potential donors are screened carefully to ensure they are healthy and able to donate.
This will ensure that:
- You can tolerate the surgical removal of a kidney and remain healthy after, with no increased health risks.
- The transplant recipient will benefit from your donor kidney.
Independent living donor advocate (ILDA)
The ILDA is a social worker who has received advanced education to be an independent and specialized advocate for living donors.
The ILDA's role is to ensure that living donors understand the entire living donor process and have had their questions answered. The ILDA will ensure that potential donors receive all the necessary information throughout all phases of the donation process.
As a potential living donor, any questions or concerns you may have about the care you receive from the transplant team may be directed to the ILDA.
How should I prepare for living-donor kidney surgery?
Your living-donor kidney transplant nurse coordinator will provide details on how to prepare for your surgery.
We ask all organ donors to take basic health measures. These will help ensure surgery goes smoothly and reduce the recipient's risk of rejecting your kidney.
Health measures include:
- Stop smoking — If you're a light smoker, please stop smoking at least one month before your kidney donation surgery. People who smoke heavily do not make ideal organ donors since smoking increases surgical risks.
- Avoid alcohol and drugs — Prior to living-donor kidney surgery, you must avoid using alcohol and drugs. We also ask that you inform your living-donor transplant nurse coordinator of any medications you are currently taking.
- Stop oral (by mouth) contraceptives — Donors should stop oral contraceptives around eight weeks before kidney donation to prevent blood clots after surgery. We strongly advise you to use other forms of birth control during this time.
Who pays for kidney donation surgery?
The recipient’s insurance and UPMC will cover the cost of the evaluation and donor operation. The donor will not be financially responsible for any part of the transplant evaluation or surgery. During the evaluation visit, a financial coordinator will meet with the donor to answer questions about the process.
Living-donor kidney transplant surgery
On the day of your living-donor kidney transplant surgery, we will admit you to the hospital.
You will meet with the kidney transplant surgeon and anesthesiologist who will:
- Review the surgery with you.
- Have you sign consent forms.
- Answer any last-minute questions.
After the paperwork, you will proceed to the operating room.
Living-donor kidney transplant surgery can take three to five hours.
Your loved ones can wait in the waiting area, where staff will provide frequent updates. After the surgery is complete, your kidney transplant surgeon will also meet with your family members.
After living-donor kidney transplant
After living-donor kidney surgery, you'll be moved to a recovery unit to make sure you do not need additional treatment. Afterward, you'll transfer to a transplant recovery floor where you may stay for a few days before going home.
Will I need to take any medication after donating my kidney?
No. You will not need to take any medicine. You will need to receive post-kidney-donation care at UPMC to make sure you heal properly.
How soon will I be able to return to work after living-donor kidney surgery?
It takes up to two months for most living kidney donors to recover fully. When you can return to work will depend on your job type.
Thinking of Becoming a Living Kidney Donor?
UPMC's kidney transplant team works with potential kidney donors and recipients throughout the entire living-donor kidney transplant process.
Before surgery, we ensure that donors can return to living full and active lives with one kidney.
If you're thinking of donating your kidney, find out more:
Why Choose UPMC for Living-Donor Kidney Transplant?
When you choose UPMC for living-donor kidney transplant care, you will receive:
- Access to experienced, board-certified specialists — Since 1988, our surgeons have performed more than 2,600 living-donor kidney transplants, making our program one of the most experienced in the nation.
- Expert care for complex cases — As one of the nation's most active and experienced transplant programs, we have extensive experience in living-donor transplants that enables us to handle some of the most complex cases.
- Personalized living-donor care — From thorough evaluation to world-class treatment, we provide a patient-centered approach to care throughout the entire transplant process. Your dedicated transplant team will guide and support you each step of the way.
By UPMC Editorial Staff. Last reviewed on 2025-12-09.