Celiac Disease

Overview
Diagnosis
Treatment

Celiac Disease

More than 2 million people in America have celiac disease, a digestive and autoimmune disorder that causes inflammation and damage to the small intestine.

Celiac disease affects people of all ages, genders and races, and it can be hereditary. Those suffering from the disease cannot tolerate gluten, a protein found in:

Wheat
Rye
Barley
Some oats

When people with celiac disease consume gluten, their immune systems attack the small intestine and damage the inner lining which is used to absorb nutrients from food. Because the body is not absorbing nutrients, people with celiac disease suffer from malnourishment and other health complications.

The UPMC Celiac Disease Center offers its patients multidisciplinary care. Our dieticians are some of the finest in the country and work with our gastroenterologists to help decrease our patients’ symptoms.

Symptoms of Celiac Disease

Symptoms of celiac disease vary from person to person. Some people with celiac disease experience no symptoms at all. However, the most common symptoms among children and adults are:

Abdominal pain
Diarrhea
Constipation

Weight loss
Nausea
Fatigue

Infants and young children with celiac disease are more likely to have digestive symptoms but can also suffer from the following:

Irritability
Stunted growth
Delayed puberty
Dental enamel defects of the permanent teeth

Adults are also susceptible to digestive symptoms, but more commonly suffer from one or more of the following:

Unexplained iron-deficiency anemia
Fatigue
Bone or joint pain
Arthritis
Bone loss or osteoporosis

Depression or anxiety
Tingling numbness in hands and feet
Seizures
Canker sores inside the mouth
Dermatitis herpetiformis, an itchy skin rash

The UPMC Celiac Disease Center is also one of the only centers in the world to have an integrated psychosocial clinic through the Visceral Inflammation and Pain (VIP) Center. The VIP team provides comprehensive assessments to help patients cope with psychological symptoms, like depression and anxiety, which is directly linked to gastrointestinal conditions.

Diagnosing Celiac Disease

If a patient is experiencing symptoms of celiac disease, a doctor will administer tests and procedures to diagnose the disease:

Blood tests measure certain antibodies produced by the immune system
Genetic tests do not prove diagnosis but will show if the patient is not suffering from celiac disease
A biopsy taken during an endoscopy, when a small tube is guided down the patient’s throat to their small intestine, can confirm celiac disease after antibodies have been found. It can also detect celiac disease when the patient is being tested for another condition.

Treating Celiac Disease

Celiac disease is chronic and there is no known cure. People living with celiac disease must consume a gluten-free diet in order to eliminate symptoms.

Gluten is sometimes hidden in processed foods so those with celiac disease are advised to always check nutrition labels and ingredients. However, a person should not begin a gluten-free diet without being diagnosed.

In addition, celiac disease should not be confused with a wheat allergy or gluten intolerance.

Celiac Disease in Children

Breastfeeding can prevent celiac disease by 50% by introducing small amounts of gluten to a baby. If your child is diagnosed with celiac disease, UPMC Celiac Disease Center is partnered with Children’s Hospital of Pittsburgh to provide a full continuum of care.