Skip to Content
800-533-8762
  • Careers
  • Newsroom
  • Health Care Professionals
  • About Us
  • Contact Us
UPMC
  • Find a Doctor
  • Conditions
  • Services
    • Frequently Searched Services
    • Frequently Searched Services
      Allergy & Immunology Behavioral & Mental Health Cancer Ear, Nose & Throat Endocrinology Gastroenterology Heart & Vascular Imaging Neurosciences Orthopaedics
      Physical Rehabilitation Plastic & Reconstructive Surgery Primary Care Senior Services Sports Medicine Telemedicine Transplant Surgery Walk-In Care Weight Management Women’s Health
      See all Services
    • Services by Region
    • Find a UPMC health care facility close to you quickly by browsing by region.
      UPMC in Western Pa. Western Pa. and New York
      Highlighted Regional Map of UPMC in Central Pa. Central Pa.
      UPMC in North Central Pa. North Central Pa.
      UPMC in Western Md. Maryland & West Virginia
    • See All Services
  • Locations
    • Locations by Type
    • Locations by Type
      UPMC hospitals
      Hospitals
      Physical Therapy
      Physical Therapy
      Urgent care
      Walk-In Care
      UPMC Outpatient Centers
      Outpatient Centers
      UPMC Imaging Services
      Imaging
      Community Health Centers
      Community Health Centers
      See All Locations
    • Locations by Region
    • Locations by Region
      UPMC in Southwest Pa. Southwest Pa.
      UPMC in North Central Pa. North Central Pa.
      UPMC in Northwest Pa and Ny. Northwest Pa. & Western N.Y.
      UPMC in West Central Pa. West Central Pa.
      Highlighted Regional Map of UPMC in Central Pa. Central Pa.
      UPMC in Western Md. Maryland & West Virginia
    • See All Locations
  • Patients & Visitors
    • Patient & Visitor Resources
    • Patient & Visitor Resources
      Patients and Visitors Resources Pay a Bill Classes & Events Health Library International Traveling Patients Medical Records
      Patient Information Patient Portals Privacy Information Shared Decision Making Visitor Information
      Man uses mobile phone
      Pay a Bill
      Nurse reviews medical chart
      Request Medical Records
  • Patient Portals
  • Find Covid-19 updates
  • Schedule an appointment
  • Request medical records
  • Pay a bill
  • Learn about financial assistance
  • Find classes & events
  • Send a patient an eCard
  • Make a donation
  • Volunteer
  • Read HealthBeat blog
  • Explore UPMC Careers
Skip to Content
UPMC
  • Find a Doctor
    • Doctor Search
  • Conditions
    • Search Conditions We Treat
  • Services
    • Frequently Searched Services
      • Heart and Vascular Services
      • Neurosciences Services
      • Orthopaedics Services
      • Primary Care Services
      • Spine Care Services
      • Sports Medicine Services
      • Transplant Services
      • Women's Health Services
      • See all Services
    • Services by Region
      • Find Care in Western Pa
      • Find Care in Central Pa
      • Find Care in North Central Pa
      • Find Care in Western Maryland
    • See All Services
  • Locations
    • Locations by Type
      • Hospitals
      • Walk-In Care
      • Imaging
      • Physical Therapy
      • Outpatient
      • Community Health Centers
      • See All Locations
    • Locations by Region
      • Central Pa.
      • Maryland and West Virginia
      • North Central Pa.
      • Northwest Pa. & Western N.Y.
      • Southwest Pa.
      • West Central Pa.
    • See All Locations
  • Patients & Visitors
    • Patient & Visitor Resources
      • Pay a Bill
      • Classes & Events
      • Health Library
      • International Traveling Patients
      • Medical Records
      • Patient Information
      • Patient Portals
      • Privacy Information
      • Shared Decision Making
      • Visitor Information
      • View All Patients and Visitors Resources
  • I Want To
    • Find Covid-19 updates
    • Schedule an appointment
    • Request medical records
    • Pay a bill
    • Learn about financial assistance
    • Find classes & events
    • Send a patient an eCard
    • Make a donation
    • Volunteer
    • Read HealthBeat blog
    • Explore UPMC Careers
  • Patient Portals
  • Careers
  • Contact Us
  • Newsroom
  • UPMC >
  • Conditions >
  • I >
  • Inflammatory Bowel Disease (IBD)

Inflammatory Bowel Disease (IBD)

Inflammatory bowel disease (IBD) refers to a group of health issues that cause inflammation in the digestive system. The most common conditions are Crohn’s disease and ulcerative colitis. The symptoms of IBD include diarrhea, fever, and stomach pain. IBD is treated with diet changes, medicine, and sometimes surgery.

Looking for Inflammatory Bowel Disease Care?

Related services:
  • Gastroenterology.
  • Primary Care.
Find a Provider

On this page:

  • What Is Inflammatory Bowel Disease?
  • What Are the Signs and Symptoms of Inflammatory Bowel Disease?
  • How Do You Diagnose Inflammatory Bowel Disease?
  • How Do You Treat Inflammatory Bowel Disease?

What Is Inflammatory Bowel Disease?

Inflammatory bowel disease (IBD) is a collective term that covers two conditions of the digestive tract: Crohn’s disease and ulcerative colitis. Both conditions cause chronic inflammation and can damage the gastrointestinal (GI) tract. IBD can have chronic symptoms or come in a series of flare-ups and periods of remission.

What are the types of inflammatory bowel disease?

Two main conditions sharing similar symptoms fall under inflammatory bowel disease:

  • Crohn’s disease (CD) is inflammation in any portion of the intestinal tract, from the mouth to the colon. The inflammation is often in patches, mainly on the small intestine, and may even reach through layers of tissue. Crohn’s disease tends to be associated with pain in the lower right quadrant of the body and presents differently depending on the region of the intestine it affects.
  • Ulcerative colitis (UC) is inflammation in the rectum or colon. This condition causes inflammation solely in the surface of the intestinal lining, which causes ulcers that bleed and produce pus. UC presents as bloody diarrhea with or without mucus. It is often associated with pain the upper or lower left quadrants of the body. Other symptoms include a recurring or constant feeling of having to evacuate your bowels, incomplete evacuation, and pain in the abdomen.

Both conditions have a genetic predisposition, meaning you are more likely to have IBD if someone in your family also has this condition. Neither ulcerative colitis nor Crohn’s disease is curable, and both can increase your risk of colorectal cancer.

How common is inflammatory bowel disease?

Inflammatory bowel disease is more common in people over age 45. More than 3 million people in the U.S. have some form of IBD.

What causes inflammatory bowel disease?

The exact cause of inflammatory bowel disease is unknown; however, the symptoms of IBD are brought on by eating and activating the digestive system. The immune system might respond too strongly to normal bacteria in the digestive system, resulting in inflammation.

Certain foods and drinks may trigger IBD, but the specifics differ for each person. For many people with IBD, high-fat foods, spicy foods, alcohol, and caffeine can trigger flare-ups. While stress might not cause flare-ups, it can worsen their effects.

Back to top

Inflammatory bowel disease risk factors

Although the cause of IBD is unknown, there are several risk factors for it. IBD can lead to severe, even life-threatening issues if left untreated.

The risk factors of IBD include:

  • Age – IBD is more likely to occur in people over 45.
  • Ethnicity – IBD is more prevalent among Hispanics, non-Hispanic whites, and Jewish people of European descent.
  • Family history – You are more likely to have IBD if someone in your family has IBD.
  • Smoking – Smokers are more likely to have IBD.

Back to top

Complications of inflammatory bowel disease

Left undiagnosed or untreated IBD can lead to many health complications, including:

  • Bowel obstruction.
  • Colon cancer.
  • Dehydration.
  • Depression and anxiety.
  • Infections in the intestinal lining.
  • Inflammation in other organs, such as the liver or pancreas.
  • Iron-deficiency anemia.
  • Kidney stones.
  • Malnutrition.
  • Open sores or tears.
  • Severe PMS and menstrual symptoms.
  • Toxic megacolon (a severe health issue where the large intestine swells and stops working).
  • Trouble getting pregnant.
  • Weak bones.

Back to top

How can I reduce my risk of inflammatory bowel disease?

IBD is not a condition that can be prevented or cured. However, the symptoms can be managed.

To prevent developing bouts of IBS, it helps if you can:

  • Avoid certain foods and drinks that trigger flare-ups.
  • Exercise on a routine basis.
  • Learn how to manage your stress.

Back to top

What Are the Signs and Symptoms of Inflammatory Bowel Disease?

The symptoms of IBD can be mild or severe and might only occur as flare-ups or could chronically affect your health.

Common symptoms include:

  • Bloating.
  • Blood in your stool.
  • Chronic abdominal pain.
  • Constipation alternating with diarrhea.
  • Fatigue.
  • Fever.
  • Gassiness.
  • Joint pain.
  • Loss of appetite.
  • Rashes.
  • Severe abdominal pain or cramping.
  • The urge to move your bowels without being able to.
  • Vomiting.
  • Weight loss.

When should I see a doctor about my inflammatory bowel disease symptoms?

If you are experiencing any of the symptoms above regularly, either chronically or intermittently, you should contact your doctor about testing for IBD. If you notice blood or mucus in your stool, you should contact your doctor immediately.

Back to top

How Do You Diagnose Inflammatory Bowel Disease?

Based on your symptoms, doctors will need to run a series of tests to learn if you have IBD.

Tests to diagnose inflammatory bowel disease

 These tests include:

  • Blood tests.
  • Colonoscopy.
  • CT scan.
  • Endoscopy.
  • Stool sample test.
  • Upper endoscopy.
  • X-rays.

Back to top

How Do You Treat Inflammatory Bowel Disease?

Unfortunately, IBD is not a curable condition, but the symptoms can be managed. In some severe cases, there are surgical options to prevent the worsening of the condition.

Key treatments for IBD include:

Dietary and lifestyle changes to treat IBD

Identifying and avoiding the foods that cause flare-ups in your symptoms is the most accessible way to manage your IBD symptoms. Exercising regularly and eating a Mediterranean, low-fiber, or low-residue diet might make it easier for your digestive system to work.

Other changes include:

  • Drinking lots of fluids – Keeps you hydrated and helps manage diarrhea.
  • Eating smaller, more frequent meals – Prevents overeating and eases digestion.
  • Finding support – Connecting with others who have IBD or talking with a therapist can help manage the emotional aspects of the condition.
  • Getting enough sleep – At least seven hours of sleep are needed to reset the body’s systems each day.
  • Reducing stress – Stress can worsen IBD symptoms. Stress management techniques like deep breathing, meditation, and mindfulness can help.
  • Taking supplements – Ask your doctor if you can benefit from supplements like calcium, folic acid, iron, vitamins D and B12, zinc, and/or probiotics.

Medication to treat IBD

Common medicine types used to treat IBD include:

  • Aminosalicylates – Also called 5-aminosalicylic acids or 5-ASA, these drugs help reduce inflammation in the digestive tract.  
  • Biologics – Made from living sources, such as humans, animals, or microorganisms, biologics block the chemicals in the immune system that trigger inflammation.
  • Corticosteroids – Strong anti-inflammatory steroids that work quickly. They are usually given in large doses at first, then the dosage is tapered (lowered), and eventually stopped.
  • Immunomodulators – Also called immunosuppressive agents, immunomodulators block the immune reaction that leads to inflammation.

Surgery for IBD

There are a few surgical options to treat severe IBD symptoms:

  • Colectomy – Removal of all or part of the colon.
  • Intestinal stricturoplasty – Surgery to widen the parts of your intestinal tract that have narrowed due to inflammation and scar tissue build-up.
  • Proctocolectomy – Removal of all or part of the colon and rectum. This surgery is usually combined with an ileostomy, which is a procedure where the ileum segment of the intestine is diverted out of an ostomy (artificial hole in the abdomen).
  • Small bowel resection – Procedure to remove a damaged segment of the small intestine. It is commonly performed to treat the complications of Crohn’s disease, like abscess, bowel obstruction, fistula, or perforation.

How effective is treatment? 

Because inflammatory bowel disease is not curable, all of these treatments and procedures are only measures to reduce the complications or symptoms of IBD. Living with ulcerative colitis or Crohn’s disease means lifelong condition management. So, while treatments can be very effective and successful in treating immediate complications of the conditions, it can also mean you may need further intervention to manage your IBD symptoms.

Back to top

  • NIH National Library of Medicine, Inflammatory Bowel Disease.
  • CDC, Inflammatory Bowel Disease (IBD) Basics.

By UPMC Editorial Team. Reviewed on 2025-10-10.

2025-10-10
2026-04-21
Inflammatory Bowel Disease (IBD)
Inflammatory bowel disease (IBD) is a group of disorders that cause inflammation in the digestive system. Crohn's disease and ulcerative colitis are the most common types of IBD.
UPMC
200 Lothrop Street Pittsburgh, PA 15213

412-647-8762 800-533-8762

Patients And Visitors
  • Find a Doctor
  • Locations
  • Pay a Bill
  • Patient & Visitor Resources
  • Disabilities Resource Center
  • Services
  • Medical Records
  • No Surprises Act
  • Price Transparency
  • Financial Assistance
  • Classes & Events
  • Health Library
Health Care Professionals
  • Physician Information
  • Resources
  • Education & Training
  • Departments
  • Credentialing
Newsroom
  • Newsroom Home
  • Inside Life Changing Medicine Blog
  • News Releases
About
  • Why UPMC
  • Facts & Stats
  • Supply Chain Management
  • Community Commitment
  • Financials
  • Supporting UPMC
  • HealthBeat Blog
  • UPMC Apps
  • UPMC Enterprises
  • UPMC Health Plan
  • UPMC International
  • Nondiscrimination Policy
Life changing is...
Follow UPMC
  • Contact Us
  • Website/Email Terms of Use
  • Medical Advice Disclaimer
  • Privacy Information
  • Active Privacy Alerts
  • Sitemap
© 2026 UPMC I Affiliated with the University of Pittsburgh Schools of the Health Sciences Supplemental content provided by WebMD Ignite. To learn more, visit webmdignite.com.
Find Care
Providers
Video Visit
Portal Login

Chat Keywords List

  • cancel or exit: Stops your conversation
  • start over: Restarts your current scenario
  • help: Shows what this bot can do
  • terms: Shows terms of use and privacy statement
  • feedback: Give us feedback
Continue
Chat with UPMC
RESTART
MENU
CLOSE